Target Details
| UniProt AC | P16499 |
|---|---|
| Gene Symbol | PDE6A |
| Protein Name | Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF01590 (GAF) PF00233 (PDEase_I) |
Summary
- Multi-target molecules 50
- Clinical molecules 0
- Avg pChEMBL 7.09
KEGG Pathways (3)
Associated Diseases (1)
Active Molecules (50)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
UJLHNYPXKZJKLV
|
10.0 | IC50 | 24 | — | |
KXCOKRBRUWINCT
|
9.9 | IC50 | 24 | — | |
KPFFPWNKWSYQFT
|
9.8 | IC50 | 24 | — | |
GOBQSCBEINUNFL
|
9.6 | IC50 | 24 | — | |
AFCWMWBOATWMJV
|
9.5 | IC50 | 24 | — | |
DKSKKVAOIPURFT
|
9.5 | IC50 | 24 | — | |
BPBDCOLBZYWXHD
|
9.0 | IC50 | 24 | — | |
FMMIDZWTNQYEIY
|
9.0 | IC50 | 24 | — | |
HIEBSPLRWFLZPT
|
8.7 | IC50 | 7 | — | |
LMZYNSBAUOTKJP
|
8.1 | IC50 | 7 | — | |
SECKRCOLJRRGGV
|
8.0 | IC50 | 16 | — | |
BNRNXUUZRGQAQC
|
7.6 | IC50 | 12 | — | |
WOUKAJYAWLIKFZ
|
7.5 | IC50 | 2 | — | |
YLBRHUHHQIYMSH
|
7.5 | IC50 | 7 | — | |
JBHLOPKIPKTRSU
|
7.4 | Ki | 4 | — | |
ZUGQSSCMJHOUMY
|
7.2 | IC50 | 4 | — | |
ILKQRTXPJWHTCQ
|
7.2 | IC50 | 7 | — | |
ZXGQTWGCVTUQHJ
|
7.1 | IC50 | 8 | — | |
IZEKFCXSFNUWAM
|
6.9 | Ki | 19 | — | |
HVDQYPSFEUUGDN
|
6.8 | IC50 | 8 | — | |
WVFZLLHYILMVBO
|
6.7 | Ki | 7 | — | |
RNLNRXGCWGOQMW
|
6.6 | Ki | 7 | — | |
WDRWBLDUZZTZRV
|
6.6 | IC50 | 8 | — | |
ANFPYGBSFPVDQM
|
6.5 | IC50 | 7 | — | |
OFZGCAMFVYIIHV
|
6.5 | IC50 | 24 | — | |
OTFYWELOCYDGRZ
|
6.5 | IC50 | 7 | — | |
YKLLPTMXZQKNGA
|
6.5 | IC50 | 7 | — | |
FGBIHGKWPVSHSO
|
6.5 | IC50 | 7 | — | |
MIATWQLLYKUWRD
|
6.5 | IC50 | 8 | — | |
REZGGXNDEMKIQB
|
6.4 | Ki | 8 | — | |
UEHYTJCPYRCAPM
|
6.4 | IC50 | 8 | — | |
CIKOPVDFPXGTDP
|
6.3 | IC50 | 8 | — | |
BWVJYTGTOWKCOX
|
6.3 | IC50 | 8 | — | |
SDYQZLQJADODFL
|
6.3 | Ki | 7 | — | |
XJCFZDNOEIPPIC
|
6.3 | IC50 | 7 | — | |
PUJFXPWIBOJQHB
|
6.2 | IC50 | 12 | — | |
KSTNYSJSCGBUFA
|
6.2 | IC50 | 6 | — | |
UEMKDTSBXWIJFQ
|
6.2 | IC50 | 7 | — | |
VFFZRVLFFCXMEW
|
6.2 | Ki | 7 | — | |
WTHIWWQIRPIFLQ
|
6.2 | IC50 | 8 | — | |
HLUWBLAYMFWHOF
|
6.1 | IC50 | 8 | — | |
RPLZXBUKXSYWDQ
|
6.1 | IC50 | 10 | — | |
RCUCFFJDNMXZAV
|
6.1 | Ki | 7 | — | |
SGZFBLCNGYGISG
|
6.1 | IC50 | 8 | — | |
QBLWGJRSTWQUGT
|
6.0 | IC50 | 8 | — | |
YAZFJAWMJDOHDF
|
6.0 | IC50 | 6 | — | |
JITUOVWOCIXEEZ
|
6.0 | IC50 | 23 | — | |
NWOYPSQSXFBTCX
|
6.0 | IC50 | 6 | — | |
OWWOVESWHWBLEI
|
6.0 | IC50 | 6 | — | |
XUVQDOKJUZEZAL
|
6.0 | IC50 | 2 | — |