Target Details
| UniProt AC | P16234 |
|---|---|
| Gene Symbol | PDGFRA |
| Protein Name | Platelet-derived growth factor receptor alpha |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF07679 (I-set) PF25305 (Ig_PDGFR_d4) PF07714 (PK_Tyr_Ser-Thr) |
Summary
- Multi-target molecules 860
- Clinical molecules 94
- Avg pChEMBL 7.24
KEGG Pathways (22)
- Cadherin signaling
- Calcium signaling pathway
- Central carbon metabolism in cancer
- Choline metabolism in cancer
- EGFR tyrosine kinase inhibitor resistance
- Endocytosis
- Focal adhesion
- Gap junction
- Glioma
- Human cytomegalovirus infection
- Integrin signaling
- JAK-STAT signaling pathway
- MAPK signaling pathway
- Melanoma
- MicroRNAs in cancer
- PI3K-Akt signaling pathway
- Pathways in cancer
- Phospholipase D signaling pathway
- Prostate cancer
- Rap1 signaling pathway
- Ras signaling pathway
- Regulation of actin cytoskeleton
Associated Diseases (4)