Target Details
| UniProt AC | P15498 |
|---|---|
| Gene Symbol | VAV1 |
| Protein Name | Proto-oncogene vav |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF00130 (C1_1) PF11971 (CAMSAP_CH) PF00169 (PH) PF00621 (RhoGEF) PF00017 (SH2) PF00018 (SH3_1) |
Summary
- Multi-target molecules 1
- Clinical molecules 1
- Avg pChEMBL 8.97
KEGG Pathways (16)
- B cell receptor signaling pathway
- Cadherin signaling
- Chemokine signaling pathway
- Fc epsilon RI signaling pathway
- Fc gamma R-mediated phagocytosis
- Focal adhesion
- IgSF CAM signaling
- Leukocyte transendothelial migration
- Lipid and atherosclerosis
- Natural killer cell mediated cytotoxicity
- Proteoglycans in cancer
- Rap1 signaling pathway
- Regulation of actin cytoskeleton
- T cell receptor signaling pathway
- Yersinia infection
- cAMP signaling pathway
Active Molecules (1)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
BQJRUJTZSGYBEZ
|
9.0 | Kd | 13 | Yes |