Target Details
| UniProt AC | P14778 |
|---|---|
| Gene Symbol | IL1R1 |
| Protein Name | Interleukin-1 receptor type 1 |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF13895 (Ig_2) PF18452 (Ig_6) PF01582 (TIR) |
Summary
- Multi-target molecules 1
- Clinical molecules 0
- Avg pChEMBL 6.14
KEGG Pathways (13)
- Amoebiasis
- Cytokine-cytokine receptor interaction
- Fluid shear stress and atherosclerosis
- Hematopoietic cell lineage
- Human T-cell leukemia virus 1 infection
- Human cytomegalovirus infection
- Inflammatory mediator regulation of TRP channels
- MAPK signaling pathway
- NF-kappa B signaling pathway
- Osteoclast differentiation
- Pathogenic Escherichia coli infection
- Shigellosis
- Th17 cell differentiation
Associated Diseases (1)
Active Molecules (1)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
BMBIKZHGTPMMMM
|
6.1 | IC50 | 14 | — |