Target Details
| UniProt AC | P13501 |
|---|---|
| Gene Symbol | CCL5 |
| Protein Name | C-C motif chemokine 5 |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF00048 (IL8) |
Summary
- Multi-target molecules 12
- Clinical molecules 0
- Avg pChEMBL 7.48
KEGG Pathways (16)
- Chagas disease
- Chemokine signaling pathway
- Cytokine-cytokine receptor interaction
- Cytosolic DNA-sensing pathway
- Epithelial cell signaling in Helicobacter pylori infection
- Herpes simplex virus 1 infection
- Human cytomegalovirus infection
- Influenza A
- Lipid and atherosclerosis
- NOD-like receptor signaling pathway
- Prion disease
- Rheumatoid arthritis
- Shigellosis
- TNF signaling pathway
- Toll-like receptor signaling pathway
- Viral protein interaction with cytokine and cytokine receptor
Associated Diseases (1)
Top Co-occurrence Targets
- CCR5 12 shared
Active Molecules (12)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
RFNTZDWBOZXHTR
|
7.8 | IC50 | 2 | — | |
DFPLYLKKYSEABD
|
7.6 | IC50 | 2 | — | |
HIEMJINKLJLCCH
|
7.6 | IC50 | 2 | — | |
IDSHXLDGGWIGBW
|
7.6 | IC50 | 2 | — | |
NTXQSFSEZXNHJY
|
7.6 | IC50 | 2 | — | |
RUGPFTCINDXZAE
|
7.5 | IC50 | 2 | — | |
FCBWQXORDQYHFI
|
7.5 | IC50 | 2 | — | |
LLEJRCRDMYBLEH
|
7.5 | IC50 | 2 | — | |
QLVOILJNRVKKRP
|
7.4 | IC50 | 2 | — | |
NTTROUGKGFNVGR
|
7.4 | IC50 | 2 | — | |
YWUQJCUUNVCNFS
|
7.3 | IC50 | 2 | — | |
IUENSEDRGKTRGA
|
7.0 | IC50 | 2 | — |