ACE — MultiTargetDB

Target Details

UniProt AC	`P12821`
Gene Symbol	ACE
Protein Name	Angiotensin-converting enzyme
Organism	Homo sapiens
Entry Name
Organism Category	Human
Pfam Domains	PF01401 (Peptidase_M2)

Summary

Multi-target molecules 233
Clinical molecules 3
Avg pChEMBL 7.47

KEGG Pathways (6)

Associated Diseases (5)

Top Co-occurrence Targets

MME 158 shared
ACE2 106 shared
ECE1 12 shared
DPP4 4 shared
MMP13 3 shared
SLC6A2 3 shared
nadE 3 shared
CPA1 3 shared
REN 3 shared
EMG1 2 shared

Active Molecules (233)

InChIKey	pChEMBL	Type	Targets	Clinical
`PFSPSDHEYBMTQM`	7.6	IC50	2	—
`WMJSQLHYOQNHIT`	7.5	IC50	2	—
`YQDOHAUNEYURLH`	7.5	IC50	2	—
`IQHFJQXJLKTGJO`	7.5	IC50	2	—
`SJZSCNBOYIWMHJ`	7.5	IC50	2	—
`BNECOBGISSOLPT`	7.5	Ki	3	—
`ICVAKVXFPOSUDK`	7.5	IC50	3	—
`YSFYVNRABGRTNY`	7.5	IC50	2	—
`CDDHYPGPHOOMFW`	7.5	IC50	2	—
`YJNWDJIIFRGLRO`	7.5	Ki	2	—
`VCPVOGSIRZPBGD`	7.5	IC50	2	—
`MKODWSWFPOSLLD`	7.5	IC50	2	—
`CRYGCPYTHSHCKP`	7.5	Ki	2	—
`CZFGWEONSMKJRA`	7.5	Ki	2	—
`HXSOGWMGAAJSIY`	7.5	Ki	2	—
`JRAQIPPUUOUHFM`	7.5	Ki	2	—
`NKTBYQHQUNEYTN`	7.5	Ki	2	—
`POIKHACBOPACCB`	7.5	Ki	2	—
`YZFDYPGDRYHPEQ`	7.5	Ki	2	—
`DVGSPMNKYPLUAT`	7.4	IC50	2	—
`ITMFWUAKJPURIP`	7.4	Ki	2	—
`PRNNUULGNBSAAT`	7.4	IC50	2	—
`QHBPFNHEJJZWMW`	7.4	IC50	2	—
`JXCFHCFAYKJVSI`	7.4	IC50	3	—
`QVLBZMKHYLEWGB`	7.4	Ki	2	—
`IAFVRFJGXZLXTJ`	7.4	IC50	2	—
`OCCYDXOFQKDGHX`	7.4	IC50	2	—
`OCCYDXOFQKDGHX`	7.4	IC50	2	—
`BNGVWMNLGADUIP`	7.4	IC50	3	—
`VAFYRBBLYXKEBH`	7.3	IC50	2	—
`YIMJMPFFIWOIDL`	7.3	IC50	2	—
`CFXDAJRKCYEWFN`	7.3	IC50	2	—
`KSDXHWOIFKMBGX`	7.3	IC50	3	—
`LPUDGHQMOAHMMF`	7.3	Ki	3	—
`WEYWTPCHMFHABR`	7.3	Ki	2	—
`HTEXKUKUMOZCFK`	7.3	IC50	2	—
`IEBMXVZQILSQHG`	7.3	IC50	3	—
`YSCAUSDTOSSZRE`	7.3	IC50	2	—
`POIKHACBOPACCB`	7.3	Ki	2	—
`ARLLTWAARBFLHJ`	7.2	IC50	2	—
`AEJMWTIBRVQCOF`	7.2	IC50	2	—
`IXIRWVIYLLRFNN`	7.2	IC50	2	—
`JXCFHCFAYKJVSI`	7.2	IC50	2	—
`PPRRVNBFLHYEOF`	7.2	IC50	2	—
`OHEMLLQWDPOUER`	7.2	IC50	3	—
`QJZUXIPDHISQFZ`	7.2	Ki	2	—
`WPGNBXOKKGNCRD`	7.2	IC50	2	—
`FTZIHGUFMWZVIM`	7.1	IC50	3	—
`DKIMDRWUHPPJGD`	7.1	IC50	2	—
`LIJZWEBJPLIHNV`	7.1	IC50	2	—