Target Details
| UniProt AC | P12236 |
|---|---|
| Gene Symbol | SLC25A6 |
| Protein Name | ADP/ATP translocase 3 |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF00153 (Mito_carr) |
Summary
- Multi-target molecules 3
- Clinical molecules 0
- Avg pChEMBL 7.22
KEGG Pathways (15)
- Alzheimer disease
- Calcium signaling pathway
- Cellular senescence
- Chemical carcinogenesis - reactive oxygen species
- Diabetic cardiomyopathy
- Human T-cell leukemia virus 1 infection
- Huntington disease
- Influenza A
- Necroptosis
- Neutrophil extracellular trap formation
- Parkinson disease
- Pathways of neurodegeneration - multiple diseases
- Prion disease
- Spinocerebellar ataxia
- cGMP-PKG signaling pathway
Active Molecules (3)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
WJEOLQLKVOPQFV
|
8.2 | Kd | 24 | — | |
MWKSRKSEWLRPBL
|
6.9 | Kd | 1075 | — | |
AAAQFGUYHFJNHI
|
6.5 | IC50 | 252 | — |