Target Details
| UniProt AC | P10721 |
|---|---|
| Gene Symbol | KIT |
| Protein Name | Mast/stem cell growth factor receptor Kit |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF00047 (ig) PF07714 (PK_Tyr_Ser-Thr) |
Summary
- Multi-target molecules 1,134
- Clinical molecules 305
- Avg pChEMBL 7.36
KEGG Pathways (11)
Associated Diseases (7)
Active Molecules (1,134)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
UUVMNPKFPGJBNX
|
9.8 | Ki | 10 | — | |
YISMQBFJYDFMAL
|
9.7 | IC50 | 46 | — | |
LYHDXABKNJMNEZ
|
9.7 | Ki | 10 | — | |
DWYRIWUZIJHQKQ
|
9.6 | IC50 | 3 | — | |
FOONBYIHFUMRSX
|
9.5 | Ki | 12 | — | |
YEPNVBNYCRGZRX
|
9.5 | Ki | 26 | — | |
XXJWYDDUDKYVKI
|
9.3 | Kd | 52 | — | |
BDPBZUHWAVABDM
|
9.3 | Ki | 11 | — | |
CTNPALGJUAXMMC
|
9.2 | Kd | 151 | — | |
DBXOMQJZSQLQED
|
9.1 | Ki | 12 | — | |
GDEJPGKNPRJNGE
|
9.1 | Ki | 6 | — | |
KROLCVQARUUHNV
|
9.1 | Ki | 12 | — | |
NSKFXNDKPCVDIN
|
9.1 | Ki | 12 | — | |
SJMFZIGFOIPNPE
|
9.1 | Ki | 10 | — | |
ZQQVWTACALNOAJ
|
9.1 | Ki | 11 | — | |
BGVQPQHIUOTLBT
|
9.0 | Kd | 6 | — | |
FPYCSQMCBIGNHK
|
9.0 | IC50 | 3 | — | |
GSURAMUGDNSWKE
|
9.0 | IC50 | 3 | — | |
HBHOKIDZSIYNGE
|
9.0 | Ki | 3 | — | |
JDQIOIVXAWOMGD
|
9.0 | IC50 | 2 | Yes | |
MCCCQFAOMZMZKE
|
9.0 | Ki | 52 | — | |
MJTPRNMULDHJJJ
|
9.0 | IC50 | 4 | — | |
QAKMQVCMEPKBHL
|
9.0 | Ki | 11 | — | |
QDOBTYVGPGFRCM
|
9.0 | Ki | 11 | — | |
QFCXANHHBCGMAS
|
9.0 | IC50 | 7 | — | |
UGOPZRICVJBSEN
|
9.0 | IC50 | 3 | Yes | |
WUWVRXPSSGTMJL
|
9.0 | IC50 | 3 | — | |
JVCWPUFNLFSKFS
|
9.0 | IC50 | 5 | — | |
ORYMWWSJZRCUSV
|
9.0 | IC50 | 7 | — | |
GWQQUSRBNJRKLG
|
8.8 | IC50 | 3 | — | |
JYSCRDCBJSBWKB
|
8.8 | IC50 | 2 | — | |
NNAMXKXTCQOZGS
|
8.8 | IC50 | 5 | Yes | |
RPDVCUCXMGWTFA
|
8.8 | Ki | 10 | — | |
ULMCFLZUGRSEQA
|
8.8 | Ki | 17 | — | |
UXQLMVSZSYZFID
|
8.8 | Ki | 12 | — | |
TXEBERLYUZPASZ
|
8.8 | IC50 | 2 | — | |
YRUDYNCGPZHXRB
|
8.7 | Kd | 6 | — | |
FRGHNLRLGIIDDA
|
8.7 | IC50 | 2 | — | |
XPQJKJDXIUJKQM
|
8.7 | IC50 | 2 | — | |
CRVJWQKUGJBXHH
|
8.7 | IC50 | 3 | — | |
DCTIKIWYRXDSOC
|
8.7 | IC50 | 2 | Yes | |
DKNUPRMJNUQNHR
|
8.7 | Kd | 33 | — | |
FGSVLADZCDNNOC
|
8.7 | Ki | 11 | — | |
GKEYKDOLBLYGRB
|
8.7 | IC50 | 3 | — | |
KSXXLYFDRDYXJK
|
8.7 | IC50 | 3 | — | |
SLCFEJAMCRLYRG
|
8.7 | Kd | 8 | Yes | |
UOOZSMNSBYVUGZ
|
8.7 | Ki | 32 | — | |
GIODDBAYPWNJIQ
|
8.7 | IC50 | 4 | — | |
IVQYCPCHHYNLKB
|
8.7 | IC50 | 3 | — | |
GVFQHBBRWBJGNU
|
8.7 | IC50 | 5 | — |