Target Details
| UniProt AC | P10415 |
|---|---|
| Gene Symbol | BCL2 |
| Protein Name | Apoptosis regulator Bcl-2 |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF00452 (Bcl-2) PF02180 (BH4) |
Summary
- Multi-target molecules 1,065
- Clinical molecules 0
- Avg pChEMBL 8.33
KEGG Pathways (43)
- AGE-RAGE signaling pathway in diabetic complications
- Adrenergic signaling in cardiomyocytes
- Amyotrophic lateral sclerosis
- Apoptosis
- Apoptosis - multiple species
- Autophagy - animal
- Chemical carcinogenesis - receptor activation
- Cholinergic synapse
- Colorectal cancer
- EGFR tyrosine kinase inhibitor resistance
- Endocrine resistance
- Epstein-Barr virus infection
- Estrogen signaling pathway
- Fluid shear stress and atherosclerosis
- Focal adhesion
- Gastric cancer
- HIF-1 signaling pathway
- Hedgehog signaling pathway
- Hepatitis B
- Herpes simplex virus 1 infection
- Human immunodeficiency virus 1 infection
- JAK-STAT signaling pathway
- Lipid and atherosclerosis
- Measles
- MicroRNAs in cancer
- NF-kappa B signaling pathway
- NOD-like receptor signaling pathway
- Necroptosis
- Neurotrophin signaling pathway
- PI3K-Akt signaling pathway
- Parathyroid hormone synthesis, secretion and action
- Pathways in cancer
- Pathways of neurodegeneration - multiple diseases
- Platinum drug resistance
- Prostate cancer
- Protein processing in endoplasmic reticulum
- Salmonella infection
- Shigellosis
- Small cell lung cancer
- Sphingolipid signaling pathway
- Toxoplasmosis
- Tuberculosis
- p53 signaling pathway
Associated Diseases (8)