Target Details
| UniProt AC | P0DTC1 |
|---|---|
| Gene Symbol | N/A |
| Protein Name | Replicase polyprotein 1a |
| Organism | Severe acute respiratory syndrome coronavirus 2 |
| Entry Name | |
| Organism Category | Pathogen |
| Pfam Domains | PF16251 (bCoV_NAB) PF11501 (bCoV_NSP1) PF12379 (bCoV_NSP3_N) PF12124 (bCoV_SUD_C) PF11633 (bCoV_SUD_M) PF09401 (CoV_NSP10) PF19211 (CoV_NSP2_N) PF19218 (CoV_NSP3_C) PF16348 (CoV_NSP4_C) PF19217 (CoV_NSP4_N) PF19213 (CoV_NSP6) PF08716 (CoV_NSP7) PF08717 (CoV_NSP8) PF08710 (CoV_NSP9) PF08715 (CoV_peptidase) PF01661 (Macro) PF05409 (Peptidase_C30) |
Summary
- Multi-target molecules 197
- Clinical molecules 0
- Avg pChEMBL 7.1
Active Molecules (197)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
LERCEIGOROJLAY
|
9.6 | IC50 | 2 | — | |
POPWPHIGQFWRDK
|
9.3 | IC50 | 2 | — | |
MEWSAFKJOGMCKZ
|
9.2 | IC50 | 2 | — | |
DFVOOMGEUDYSTE
|
9.1 | IC50 | 2 | — | |
WVXFUFQTNVWHME
|
9.0 | IC50 | 2 | — | |
RZTKCADKVFEBSP
|
9.0 | IC50 | 2 | — | |
TXFALORVHGHNIZ
|
9.0 | Ki | 2 | — | |
GSUNDMAZJLWTIT
|
8.7 | Ki | 2 | — | |
UGXSZZAITMURED
|
8.7 | IC50 | 2 | — | |
AWSZFCNWIVMPPT
|
8.5 | Ki | 2 | — | |
LOFFTBAELMOYKZ
|
8.5 | Ki | 2 | — | |
MMVYUHFDLZLNDJ
|
8.5 | IC50 | 2 | — | |
QZQMFRGAGVCQAU
|
8.5 | Ki | 2 | — | |
QNLMYJJUQPZSSI
|
8.5 | IC50 | 2 | — | |
FBDZPOPZZIODCH
|
8.4 | Ki | 2 | — | |
PXPFKYBINQAOCO
|
8.4 | Ki | 2 | — | |
YFAVHMGYTFULDO
|
8.4 | Ki | 2 | — | |
CJXNCBSSADROTD
|
8.3 | Ki | 2 | — | |
MXEGAMGMDDENAC
|
8.3 | Ki | 2 | — | |
WAXJMBFCXYZEEF
|
8.3 | IC50 | 2 | — | |
HSSWPCDEWPTIQS
|
8.3 | IC50 | 2 | — | |
ILOODQHBNBJAAG
|
8.2 | IC50 | 2 | — | |
ULEIWGQRBVSCTG
|
8.2 | Ki | 2 | — | |
RRGARHLRSSYTCB
|
8.2 | IC50 | 2 | — | |
RAAXPKDUFYAXAD
|
8.2 | IC50 | 2 | — | |
RHFOTHRIPKQIDW
|
8.2 | IC50 | 2 | — | |
ULEIWGQRBVSCTG
|
8.2 | Ki | 2 | — | |
WUMUSTXWZPBYJT
|
8.2 | Ki | 2 | — | |
DDNKJVYYJPDFOE
|
8.1 | IC50 | 2 | — | |
QFTTVHGJIGPMTG
|
8.1 | IC50 | 2 | — | |
VDPJORBKOLOGMZ
|
8.1 | IC50 | 2 | — | |
DAVWSCGJIBGBHZ
|
8.1 | IC50 | 2 | — | |
ALCYYDYSILTTKJ
|
8.1 | IC50 | 2 | — | |
PDQAUBWJYWYCIF
|
8.0 | IC50 | 2 | — | |
KSBJTEAOFRKHIW
|
8.0 | IC50 | 2 | — | |
KSSDFKAUXACCMX
|
8.0 | IC50 | 2 | — | |
SVOCCYIUNITIHL
|
8.0 | IC50 | 2 | — | |
JXGIYKRRPGCLFV
|
8.0 | IC50 | 2 | — | |
UOAJBSPQDBHHRC
|
8.0 | IC50 | 2 | — | |
LIENCHBZNNMNKG
|
7.9 | IC50 | 2 | — | |
SMQQOJDQJBWRCU
|
7.9 | IC50 | 2 | — | |
IYZRWOMTSMYRCM
|
7.9 | Ki | 2 | — | |
QJCAWERZKXLFIJ
|
7.9 | Ki | 2 | — | |
FTIFIZZEWIBTMR
|
7.8 | IC50 | 2 | — | |
NJXPUSRCRCOWEQ
|
7.8 | IC50 | 2 | — | |
QMOLFHLCHURCHA
|
7.8 | IC50 | 2 | — | |
UTSXCJSXSSVXHI
|
7.8 | Ki | 2 | — | |
MJZNRHTYZRSATJ
|
7.8 | IC50 | 2 | — | |
AQACCMRPIZQLDS
|
7.8 | Ki | 2 | — | |
NFXZAFCZOMISJH
|
7.7 | IC50 | 2 | — |