Target Details
| UniProt AC | P0C869 |
|---|---|
| Gene Symbol | PLA2G4B |
| Protein Name | Cytosolic phospholipase A2 beta |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF00168 (C2) PF18695 (cPLA2_C2) PF01735 (PLA2_B) |
Summary
- Multi-target molecules 3
- Clinical molecules 0
- Avg pChEMBL 7.22
KEGG Pathways (23)
- Arachidonic acid metabolism
- Choline metabolism in cancer
- Ether lipid metabolism
- Fc epsilon RI signaling pathway
- Fc gamma R-mediated phagocytosis
- Glutamatergic synapse
- Glycerophospholipid metabolism
- GnRH signaling pathway
- Inflammatory mediator regulation of TRP channels
- Linoleic acid metabolism
- Long-term depression
- MAPK signaling pathway
- Metabolic pathways
- Necroptosis
- Ovarian steroidogenesis
- Oxytocin signaling pathway
- Phospholipase D signaling pathway
- Platelet activation
- Ras signaling pathway
- Serotonergic synapse
- VEGF signaling pathway
- Vascular smooth muscle contraction
- alpha-Linolenic acid metabolism
Active Molecules (3)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
BBWMRBSEGFTSQC
|
7.8 | IC50 | 2 | — | |
HJJQCMPZMWKMPM
|
7.8 | IC50 | 2 | — | |
PLWROONZUDKYKG
|
6.1 | IC50 | 3 | — |