Target Details
| UniProt AC | P0AES4 |
|---|---|
| Gene Symbol | gyrA |
| Protein Name | DNA gyrase subunit A |
| Organism | Escherichia coli (strain K12) |
| Entry Name | |
| Organism Category | Pathogen |
| Pfam Domains | PF03989 (DNA_gyraseA_C) PF00521 (DNA_topoisoIV) |
Summary
- Multi-target molecules 348
- Clinical molecules 0
- Avg pChEMBL 7.04
Active Molecules (348)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
AMZRICVWDUXVKG
|
9.7 | IC50 | 2 | — | |
XDNHEUBCRLLUGV
|
9.6 | IC50 | 2 | — | |
QPGWEXKHWNTZRP
|
9.5 | IC50 | 2 | — | |
MMBMAYXIOMLWKL
|
9.5 | IC50 | 2 | — | |
DFAPUBLMKMWKJW
|
9.4 | IC50 | 2 | — | |
FWKBFPFKHVTISW
|
9.4 | IC50 | 2 | — | |
LATAAOVJXDTATP
|
9.4 | IC50 | 2 | — | |
NCCOVWJYFCYUSR
|
9.3 | IC50 | 2 | — | |
RNUUNKSRXQMFEG
|
9.3 | IC50 | 2 | — | |
DLUMOHMZOXFGIP
|
9.2 | IC50 | 2 | — | |
QZIJJNIKWHDBBY
|
9.2 | IC50 | 2 | — | |
PFOYWKADLSSSMC
|
9.2 | IC50 | 2 | — | |
DFZMJDOPWZIKHC
|
9.1 | IC50 | 2 | — | |
QJJVAUMJKWWKTD
|
9.1 | IC50 | 2 | — | |
NNLNDKUMTATEBI
|
9.0 | IC50 | 2 | — | |
ZTLWUFVREYDLAR
|
9.0 | IC50 | 2 | — | |
ACSDSFPAGHERCC
|
9.0 | IC50 | 2 | — | |
WTFQQLOYNICKHN
|
8.9 | IC50 | 2 | — | |
GRBYGGVWBJIBGB
|
8.8 | IC50 | 2 | — | |
VUXYPRAXFABKBH
|
8.8 | IC50 | 2 | — | |
JNESVCTVJBHBIH
|
8.7 | IC50 | 2 | — | |
KVRPVRSOABUSHO
|
8.7 | IC50 | 2 | — | |
LFRYDJJYXDOEEY
|
8.7 | IC50 | 2 | — | |
HNHYKQGVQWJFTI
|
8.7 | IC50 | 2 | — | |
KZLIXQLUWDBFGB
|
8.6 | IC50 | 2 | — | |
LKBSRDKXQBJKNA
|
8.6 | IC50 | 2 | — | |
PLDCYHQOMRSBAP
|
8.6 | IC50 | 2 | — | |
NGIBZDCHPGHNHN
|
8.4 | IC50 | 2 | — | |
VWGVZRSKDSKOCX
|
8.4 | IC50 | 3 | — | |
GOHJBPSSKHBQRF
|
8.4 | IC50 | 2 | — | |
GBQZRFCGAJTKDG
|
8.3 | IC50 | 4 | — | |
GYAPFWUJHNYJOH
|
8.3 | IC50 | 2 | — | |
FKCGKEHVIVGGDU
|
8.3 | Ki | 2 | — | |
VJBJRURYRWMPOS
|
8.3 | Ki | 3 | — | |
KTDQGQFRRTZMBJ
|
8.3 | IC50 | 2 | — | |
ASLMIDYEWPPSGH
|
8.2 | Ki | 3 | — | |
CWLNVKFAQINOMH
|
8.2 | Ki | 2 | — | |
WXDPTIXOZFOBQT
|
8.2 | IC50 | 2 | — | |
YJGCQIKMBDWQSU
|
8.2 | IC50 | 4 | — | |
MOSDWLNSTVBDPJ
|
8.2 | IC50 | 2 | — | |
JPIPEYYUZKTTCM
|
8.1 | IC50 | 2 | — | |
UMTBCDLZQQIIBT
|
8.1 | IC50 | 2 | — | |
UGPYVSGYCORXOH
|
8.1 | IC50 | 2 | — | |
WWSSIVALOHLUTG
|
8.1 | IC50 | 2 | — | |
DBXSXNHVESUPOA
|
8.0 | IC50 | 2 | — | |
AAWYAFMPUFDEST
|
8.0 | IC50 | 2 | — | |
YJGCQIKMBDWQSU
|
8.0 | IC50 | 4 | — | |
TWQUSFPXFBUZAU
|
8.0 | IC50 | 2 | — | |
UMVFQZONUAUFGC
|
8.0 | IC50 | 2 | — | |
GEZPDKBNSBNCLH
|
7.9 | IC50 | 2 | — |