Target Details
UniProt ACP0A017
Gene SymbolfolA
Protein NameDihydrofolate reductase
OrganismStaphylococcus aureus
Entry Name
Organism Category Pathogen
Pfam Domains PF00186 (DHFR_1)
UniProt
Summary
  • Multi-target molecules 96
  • Clinical molecules 0
  • Avg pChEMBL 8.88
Top Co-occurrence Targets
Active Molecules (96)
InChIKey pChEMBL Type Targets Clinical
RLRIWYVVMLSWOC 11.7 Ki 2 —
YXGIUKWLVPBVRP 11.3 Ki 2 —
QSAANSVYWZHQKA 11.2 Ki 2 —
KAWYXCRRDRVXKM 11.1 Ki 2 —
ATVFRKJIVAFJQN 11.0 Ki 2 —
KXPADQKFKCAVSF 11.0 Ki 2 —
WSVACSSBUCFLCD 11.0 Ki 2 —
NWQMGGJACYQJSH 10.9 Ki 2 —
IPQFUDKAKIGJNN 10.7 Ki 2 —
KDHIRSJXSHFBMF 10.7 Ki 2 —
KBZJKRXRDPRBNM 10.7 Ki 2 —
MLRYLGRISSFLSZ 10.7 Ki 2 —
IRBPSRDQINBHFJ 10.7 Ki 2 —
BRWUKGGEWWXVMJ 10.6 Ki 2 —
FGWXTZGZPLKOKM 10.6 Ki 2 —
DYQBRXOQGFCHCN 10.6 Ki 2 —
UHLOWIAOTVVNJB 10.6 Ki 2 —
ZSJCDAXDBJWWDN 10.5 Ki 2 —
FVPPAKFCBJHPMM 10.4 Ki 2 —
CQSLHFQAOFDXSO 10.0 Ki 2 —
IYGGBRFBQQVMSV 9.9 Ki 2 —
XDUKCBYHRBOIIW 9.9 Ki 2 —
AKOLUXJGSSGNIO 9.8 Ki 2 —
WHHHBZDVDZWFFO 9.8 Ki 2 —
AVUIUMWUDWCQNC 9.7 Ki 2 —
YZUAKSJUXZOMNM 9.7 Ki 2 —
BDVALXKNVWZHIQ 9.6 Ki 2 —
MDSKHVBXATUZID 9.5 Ki 2 —
UGJMRAQTQALEME 9.5 Ki 2 —
PQJCTIWOMJSEJF 9.4 Ki 2 —
CDDUFXDZAGJSTL 9.4 Ki 2 —
NFUZPVBLDCGSHI 9.4 Ki 2 —
OCMSAMCSELNFPL 9.3 Ki 2 —
FFCMYKPNNBWSOB 9.3 Ki 2 —
KHXQSOCPVWGFGA 9.3 Ki 2 —
FFTBXPJZLDTUDN 9.2 Ki 2 —
PMYSHQIRGNMQPJ 9.2 Ki 2 —
LRLRSANUFXZHLP 9.2 Ki 2 —
COSWOOIXZCPISM 9.2 Ki 2 —
QIAAYDXVTJFGSV 9.2 Ki 2 —
HYKSNPURZZNCNE 9.1 Ki 2 —
YCEDXTDKSNASDG 9.1 Ki 2 —
VHYYHLWFOUDYCI 9.1 Ki 2 —
JBQLSAAGUSPRCE 9.1 Ki 2 —
OYIKUBCUDZBNAM 9.1 Ki 2 —
XNKZSTYYGUUJMG 9.0 Ki 2 —
HFWXNEFGEGPRCI 8.9 Ki 2 —
NUIZNEMWHDKGNI 8.9 Ki 2 —
GONMKGVNDZCXFL 8.8 Ki 2 —
ZWUMGQPKPLFJSY 8.8 Ki 3 —
2D structure