Target Details
| UniProt AC | P09210 |
|---|---|
| Gene Symbol | GSTA2 |
| Protein Name | Glutathione S-transferase A2 |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF00043 (GST_C) PF02798 (GST_N) |
Summary
- Multi-target molecules 2
- Clinical molecules 0
- Avg pChEMBL 8.3
KEGG Pathways (12)
- Chemical carcinogenesis - DNA adducts
- Chemical carcinogenesis - reactive oxygen species
- Chemical carcinogenesis - receptor activation
- Drug metabolism - cytochrome P450
- Drug metabolism - other enzymes
- Fluid shear stress and atherosclerosis
- Glutathione metabolism
- Hepatocellular carcinoma
- Metabolic pathways
- Metabolism of xenobiotics by cytochrome P450
- Pathways in cancer
- Platinum drug resistance
Top Co-occurrence Targets
- MDM2 2 shared
Active Molecules (2)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
FBKFDSUZBVDZIX
|
8.3 | IC50 | 2 | — | |
FBKFDSUZBVDZIX
|
8.3 | IC50 | 2 | — |