Target Details
UniProt ACP08631
Gene SymbolHCK
Protein NameTyrosine-protein kinase HCK
OrganismHomo sapiens
Entry Name
Organism Category Human
Pfam Domains PF07714 (PK_Tyr_Ser-Thr) PF00017 (SH2) PF00018 (SH3_1)
UniProt
Summary
  • Multi-target molecules 379
  • Clinical molecules 191
  • Avg pChEMBL 7.22
KEGG Pathways (3)
Associated Diseases (1)
Top Co-occurrence Targets
Active Molecules (379)
InChIKey pChEMBL Type Targets Clinical
POLFXOSYBGYACO 7.4 IC50 2 —
BHIWBHXJQRREGM 7.4 IC50 4 Yes
JDOVRLNHIYWZKZ 7.4 IC50 7 Yes
MNJNKKYCZKBVRY 7.4 IC50 10 Yes
PSYXHVWBVRRNHD 7.4 IC50 11 Yes
ALAFDZTZJAKGIG 7.4 IC50 2 —
IVZNWJUHDBLKKT 7.4 IC50 2 —
REFXTMLPVWSINW 7.4 IC50 2 —
VPSLBUMYCILBRD 7.4 IC50 8 Yes
OBLWMYNSTHSSDS 7.4 IC50 6 Yes
MPUATQFVQOUAJF 7.3 IC50 6 Yes
OAILDJYOGMMAOQ 7.3 IC50 3 —
SHMSECDXWNWTEF 7.3 IC50 4 —
KLQFKOVDEHUNHU 7.3 IC50 10 Yes
MJALZBJFTIQSSR 7.3 IC50 12 Yes
FASPJDRKOSUHHS 7.3 IC50 10 Yes
IBHXVVYFEIGWLJ 7.3 IC50 4 —
TYCSETQHBQUZAZ 7.3 IC50 3 —
MIMOHMCANSGXIG 7.3 IC50 15 —
XPIADKIXMMYTSD 7.3 IC50 5 Yes
OWRXHGAFWZFFCW 7.3 Ki 113 —
RTDCVLCTBQDLBW 7.3 IC50 4 —
MRZVUZUMBCEAGI 7.3 IC50 12 Yes
VOIHJDKJPGOZPU 7.3 IC50 4 —
DORRCVAXQFZOLU 7.3 IC50 2 —
SNHKARUQVBJTQS 7.3 IC50 11 Yes
UORAPQCBWYIISR 7.3 IC50 13 —
UORAPQCBWYIISR 7.3 IC50 12 —
BCNXUFFSRWFFQA 7.3 IC50 5 Yes
BAIXSQGNLALLTR 7.3 IC50 4 —
NJKRMPNUGZAMJN 7.3 IC50 5 —
IVPZQVJSLCFTTO 7.2 IC50 10 Yes
RCFMYOVNMVCRHQ 7.2 IC50 5 Yes
RCPOMEUGBNHAFX 7.2 IC50 2 —
FQXQXOYNTXHBKK 7.2 IC50 7 —
LXWKVQVKYRGEKE 7.2 IC50 6 Yes
HKZFLRBSIHJRCV 7.2 IC50 2 —
QASQEQBXMMXTAK 7.2 IC50 3 —
DORRCVAXQFZOLU 7.2 IC50 2 —
GRWJFKQBVQNWQW 7.2 IC50 10 Yes
UOJUQBSCCIRCHS 7.2 IC50 4 Yes
YJNVZAXZUDOAAI 7.2 IC50 10 Yes
DUSWCXDALWVDSK 7.2 IC50 5 Yes
WYYDKVUNYRLXHX 7.2 IC50 4 Yes
DAXOOIRHYYCDDH 7.2 IC50 10 Yes
POLFXOSYBGYACO 7.1 IC50 2 —
XLRGWOQAKMIFSL 7.1 IC50 2 —
DYEJYFAQYRMVFS 7.1 IC50 9 Yes
RXNGGTYNZUEFOM 7.1 IC50 8 Yes
VVLOLXBDTFEURK 7.1 IC50 10 Yes
2D structure