Target Details
UniProt ACP08631
Gene SymbolHCK
Protein NameTyrosine-protein kinase HCK
OrganismHomo sapiens
Entry Name
Organism Category Human
Pfam Domains PF07714 (PK_Tyr_Ser-Thr) PF00017 (SH2) PF00018 (SH3_1)
UniProt
Summary
  • Multi-target molecules 379
  • Clinical molecules 191
  • Avg pChEMBL 7.22
KEGG Pathways (3)
Associated Diseases (1)
Top Co-occurrence Targets
Active Molecules (379)
InChIKey pChEMBL Type Targets Clinical
UVFCDQJUKYMBAZ 7.8 IC50 10 Yes
IVMXZQAMEUPQFS 7.7 IC50 2 —
XLRGWOQAKMIFSL 7.7 IC50 2 —
YEXAEGWRSZOFGW 7.7 IC50 4 —
YKDLGDBIORZVLP 7.7 IC50 10 Yes
HKSZLNNOFSGOKW 7.7 Kd 213 —
JCMWWPAJCOQLAF 7.7 IC50 11 Yes
UBJGLXSFXKIIFY 7.7 IC50 12 Yes
YQPHBBQBBMIYLO 7.7 IC50 6 Yes
LVSWEGNPHRUXSW 7.7 IC50 3 —
MRZVUZUMBCEAGI 7.7 IC50 11 Yes
AUCMAJMDOAHHEL 7.7 IC50 4 —
PGQWALGGBUYLQF 7.7 IC50 12 —
FAWGCSGOLCHXBH 7.6 IC50 11 Yes
JMQDNYBBUSYJKT 7.6 IC50 3 —
MWYBBCLGEHZSCP 7.6 IC50 11 Yes
REFXTMLPVWSINW 7.6 IC50 2 —
MFRGGAROFRXKRT 7.6 IC50 10 Yes
WHKSAKSSQHTIKP 7.6 IC50 4 —
XLRGWOQAKMIFSL 7.6 IC50 2 —
FHNLPTRXVQOXQO 7.6 IC50 11 Yes
IMLFSAULIJRURD 7.6 IC50 2 —
ATSRNUWJDQUCNU 7.6 IC50 3 —
CRPUDAVZTZIKMJ 7.6 IC50 7 Yes
VBUMOGXFBGYXDV 7.6 IC50 11 Yes
ZNGVEWWGDVLDRD 7.6 IC50 2 —
INIPJCMUHKXHJQ 7.6 IC50 6 Yes
KUUPATHXUAIQFZ 7.6 IC50 2 —
DVKQQTIKAXKTET 7.6 IC50 2 —
CHPHDLQQSCKHOK 7.5 IC50 8 Yes
GDQTYFYNHJDRBD 7.5 IC50 2 —
QAAYUMBDRYKVMM 7.5 IC50 3 —
MWKSRKSEWLRPBL 7.5 Kd 1075 —
BJMXICGJKUALLN 7.5 IC50 8 —
LELWDBPLERONSZ 7.5 IC50 2 —
QNABDSWBQJKBHK 7.5 IC50 45 —
ULPBTMCLMXCXEB 7.5 IC50 11 Yes
XNODQMMIMXSTMX 7.5 IC50 12 Yes
BCWVVERKADMJGG 7.5 IC50 3 Yes
FILQIUCXPQZUON 7.5 IC50 5 Yes
CXQHYVUVSFXTMY 7.5 Kd 154 —
LXURGGKEOPHREO 7.5 IC50 13 —
NVHKWMBHTXQWRP 7.5 IC50 9 Yes
UEFCSGDOOJJXTN 7.5 IC50 46 —
XOKCNIACFBBJGV 7.5 IC50 11 Yes
INGLCIWCZSLENQ 7.5 IC50 2 —
JSGRAJRLMWHOTJ 7.5 IC50 7 Yes
QBPMDFDPUIVKQA 7.5 IC50 11 Yes
BMKJTSUIIWPPHM 7.4 IC50 4 —
POLFXOSYBGYACO 7.4 IC50 2 —
2D structure