Target Details
UniProt ACP08253
Gene SymbolMMP2
Protein Name72 kDa type IV collagenase
OrganismHomo sapiens
Entry Name
Organism Category Human
Pfam Domains PF00040 (fn2) PF00045 (Hemopexin) PF00413 (Peptidase_M10)
UniProt
Summary
  • Multi-target molecules 2,719
  • Clinical molecules 1966
  • Avg pChEMBL 7.69
KEGG Pathways (11)
Associated Diseases (3)
Top Co-occurrence Targets
Active Molecules (2,719)
InChIKey pChEMBL Type Targets Clinical
MHIFGXNSNUWQOT 9.4 pIC50 3 Yes
NVNGYUBMJMOHQL 9.4 pIC50 6 Yes
PGEMRSCSFPLCBF 9.4 pIC50 8 Yes
QBWALRVIJDSECI 9.4 pIC50 5 Yes
QVCXUWWKONKLBL 9.4 pIC50 6 Yes
SWRNCXLTVBBIMK 9.4 pIC50 7 Yes
SYYRIPAKWJBIOW 9.4 pIC50 8 Yes
UBBBKPVDKLDZNE 9.4 pIC50 7 Yes
USIBDKCJHKIPNX 9.4 pIC50 6 Yes
VPXAENCQUJDPFF 9.4 IC50 4 —
XJMLKUIRAXOATH 9.4 pIC50 7 Yes
XJNFMEAYBQFDAS 9.4 IC50 4 —
YBRVBUDXSMPLGQ 9.4 pIC50 5 Yes
YUWSFQQPCKKPJG 9.4 pIC50 9 Yes
OCSMOTCMPXTDND 9.4 pIC50 14 Yes
PKVXJRTWUNPBJP 9.4 pIC50 6 Yes
PKVXJRTWUNPBJP 9.4 IC50 4 —
FYGGOGPIPBSHEF 9.4 pIC50 4 Yes
HUVXWBYSMDRXQZ 9.4 pIC50 2 Yes
OZKMQEXIBBMJLW 9.4 IC50 3 —
BTMSEVQRJBBBAY 9.4 IC50 3 —
DNWSNDYODYMMSH 9.4 IC50 3 —
CBYPWAIEESKRSM 9.4 pIC50 4 Yes
JBXOGQUSYPCSQK 9.4 pIC50 4 Yes
LEFXWKHWSSYLEF 9.4 pIC50 2 Yes
BYBOLCACCXBYNF 9.3 pIC50 4 Yes
OKGPERFMUXABQD 9.3 pIC50 4 Yes
ZIKBROOIDUARGQ 9.3 IC50 3 —
ZODGWBSBSVHUNW 9.3 pIC50 2 Yes
AMOCYMNNMVOHOG 9.3 pIC50 6 Yes
BIHFHTLMZBLJAX 9.3 pIC50 4 Yes
DSBXKNRWNDALKK 9.3 pIC50 4 Yes
FIAWLFURFKPROF 9.3 pIC50 7 Yes
IOLRUMINDIUCLJ 9.3 pIC50 8 Yes
KBZNOZAJAJRTII 9.3 pIC50 10 Yes
KKVTZTBYJGHGCO 9.3 pIC50 8 Yes
KYOFVPKPPTUVKK 9.3 pIC50 8 Yes
LFOGEPKUSWRLCL 9.3 pIC50 7 Yes
NKHJMAWHLPBSOA 9.3 Ki 5 —
OECFBMNWNGPPFC 9.3 pIC50 6 Yes
PRCRNUDMWULKSO 9.3 pIC50 7 Yes
SNMQJFHUOZBSDS 9.3 Ki 5 —
WFGLKKYZDCKZGM 9.3 IC50 2 —
WUGYYDAXBPEKAI 9.3 IC50 4 —
XFILPEOLDIKJHX 9.3 pIC50 12 Yes
ZHIRJJYNGRGHQQ 9.3 pIC50 6 Yes
BOHIPQBVCFMFFK 9.3 pIC50 4 Yes
MAARMQUENBUSOG 9.3 IC50 2 —
MJYMJQBCXIIWTG 9.3 pIC50 2 Yes
SMZZZWJJIWYSNC 9.3 pIC50 4 Yes
2D structure