Target Details
UniProt ACP08253
Gene SymbolMMP2
Protein Name72 kDa type IV collagenase
OrganismHomo sapiens
Entry Name
Organism Category Human
Pfam Domains PF00040 (fn2) PF00045 (Hemopexin) PF00413 (Peptidase_M10)
UniProt
Summary
  • Multi-target molecules 2,719
  • Clinical molecules 1966
  • Avg pChEMBL 7.69
KEGG Pathways (11)
Associated Diseases (3)
Top Co-occurrence Targets
Active Molecules (2,719)
InChIKey pChEMBL Type Targets Clinical
KNCYWVRUUBOHGE 9.5 pIC50 7 Yes
KOPIIXVBCHXDHO 9.5 pIC50 8 Yes
LTCNKRUYOJZZJO 9.5 pIC50 7 Yes
MOODLLAARDEUNJ 9.5 pIC50 6 Yes
NWFAIXPOXVQZQD 9.5 Ki 4 —
OBJBBLBMOOBABD 9.5 pIC50 8 Yes
OONXADPQRATYFL 9.5 pIC50 5 Yes
PFIVDCYVKKFLEU 9.5 pIC50 5 Yes
PUHDBKGWNNZTBP 9.5 pIC50 8 Yes
QRDYOYPORKWZCP 9.5 pIC50 6 Yes
VMWGPLRCSWOQJR 9.5 pIC50 5 Yes
YGJCNDHMYMIUBJ 9.5 pIC50 4 Yes
YVUNEHSVUBACDW 9.5 pIC50 6 Yes
ZUICQLWFCKUDMO 9.5 pIC50 2 Yes
RRLGEVWMENCJGJ 9.5 pIC50 6 Yes
SBKWBGSLOANRHJ 9.5 IC50 3 —
LSWGUPLJLWZCIM 9.5 pIC50 4 Yes
ABTPKZSVAHUDFA 9.5 pIC50 5 Yes
GSMKHTZLWUPIAS 9.5 pIC50 2 Yes
QHHHTEGVVKPDKH 9.5 IC50 6 —
WXNWNNKHEJMQOM 9.5 pIC50 8 Yes
LPZWIAVKYXCHGC 9.5 pIC50 7 Yes
YJNJISQXBXDEOV 9.5 pIC50 4 Yes
GSWRTFGMHRKLKT 9.5 pIC50 14 Yes
IAPIGLKJGZQTIG 9.5 pIC50 4 Yes
RDFQXFRQTOWZEQ 9.5 pIC50 8 Yes
VWWHTVYUWIWLPA 9.5 pIC50 3 Yes
YDSGUUACYYBPLW 9.5 IC50 4 —
UWWZSLPTPKEDCJ 9.4 IC50 2 —
UWWZSLPTPKEDCJ 9.4 pIC50 2 Yes
WVPKYEATTXWJLC 9.4 IC50 5 —
QVHQLFLTQMCYLJ 9.4 pIC50 6 Yes
XAHWTAYXASVGFG 9.4 pIC50 3 Yes
OFKCKYMJSALCIS 9.4 pIC50 3 Yes
RVKPGECPCLBLDB 9.4 pIC50 10 Yes
YBTXAIOMVIXCOD 9.4 pIC50 5 Yes
BUOKQWSUTKFXOW 9.4 pIC50 6 Yes
CYBDDZKSRZPTQR 9.4 pIC50 6 Yes
FKICHBNUXJBKPB 9.4 pIC50 5 Yes
FNURWSLLBXZLRC 9.4 pIC50 7 Yes
GAQJSKIBXSLAJK 9.4 pIC50 6 Yes
GWZMHEYDUOAMNJ 9.4 pIC50 6 Yes
GXZSIAVJNPWNMR 9.4 pIC50 7 Yes
HGCZRPPCNXJXAB 9.4 pIC50 7 Yes
ITDDXQSXMTUIFM 9.4 pIC50 7 Yes
JBWUJRFOXXRXHG 9.4 pIC50 5 Yes
JRJPXBUCHQFJHU 9.4 pIC50 6 Yes
KLWUGXOQJJWEBZ 9.4 Ki 5 —
KXEGEKRSCUZQMH 9.4 pIC50 5 Yes
LFOGEPKUSWRLCL 9.4 pIC50 7 Yes
2D structure