Target Details
| UniProt AC | P08238 |
|---|---|
| Gene Symbol | HSP90AB1 |
| Protein Name | Heat shock protein HSP 90-beta |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF13589 (HATPase_c_3) PF00183 (HSP90) |
Summary
- Multi-target molecules 602
- Clinical molecules 0
- Avg pChEMBL 7.02
KEGG Pathways (15)
- Antigen processing and presentation
- Chemical carcinogenesis - receptor activation
- Estrogen signaling pathway
- Fluid shear stress and atherosclerosis
- IL-17 signaling pathway
- Lipid and atherosclerosis
- NOD-like receptor signaling pathway
- Necroptosis
- PI3K-Akt signaling pathway
- Pathways in cancer
- Progesterone-mediated oocyte maturation
- Prostate cancer
- Protein processing in endoplasmic reticulum
- Salmonella infection
- Th17 cell differentiation
Active Molecules (602)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
BASLFXHBMHSLDF
|
7.5 | IC50 | 2 | — | |
JXPCDMPJCKNLBY
|
7.5 | IC50 | 2 | — | |
RVNZKZKYJIULFG
|
7.5 | Kd | 2 | — | |
SECQDSIPIFHPOE
|
7.5 | IC50 | 2 | — | |
UXGROXSBDPYMIT
|
7.5 | IC50 | 2 | — | |
WSMQUUGTQYPVPD
|
7.5 | IC50 | 3 | — | |
RNLVKRYMKWCANV
|
7.5 | IC50 | 2 | — | |
YFLPZTYFEBETPU
|
7.5 | IC50 | 2 | — | |
BJCKPFJLXXWTKA
|
7.5 | IC50 | 2 | — | |
GAGDTKJJVCLACJ
|
7.5 | IC50 | 3 | — | |
JLIRVZVVCCIAKG
|
7.5 | IC50 | 2 | — | |
KYKVIKAAJZSJSE
|
7.5 | IC50 | 2 | — | |
QUODKSAJAYXMND
|
7.5 | IC50 | 2 | — | |
VUQDPFXQYOUHGL
|
7.5 | IC50 | 2 | — | |
VYPXNVDEYQFURM
|
7.5 | IC50 | 2 | — | |
JWHMBQDDBSHXGL
|
7.5 | IC50 | 2 | — | |
AUPWYWWGBFAOEI
|
7.5 | IC50 | 2 | — | |
NBORIEUQDSFVFQ
|
7.5 | IC50 | 2 | — | |
BHGPLPAZSUBWME
|
7.5 | Kd | 2 | — | |
GHMZDEVGWDRXIS
|
7.5 | IC50 | 3 | — | |
ONHNSNLGKLENBX
|
7.5 | IC50 | 2 | — | |
SSSYFSSFICDYEI
|
7.5 | Kd | 2 | — | |
YUMPZOGCTVEPBT
|
7.5 | IC50 | 2 | — | |
AYOPPAMXTHNWFI
|
7.5 | IC50 | 2 | — | |
GVNFOZYVKKSCJY
|
7.5 | IC50 | 2 | — | |
ICWIHFMEULLYAE
|
7.5 | IC50 | 2 | — | |
IQGDGZXLNYMLGJ
|
7.5 | IC50 | 2 | — | |
LISCITSDKNZCQR
|
7.5 | Kd | 2 | — | |
MTYVLBLRSSNXRT
|
7.5 | Kd | 2 | — | |
RWORIWVOIKMLHF
|
7.5 | IC50 | 2 | — | |
XRFHWSYKRFEPRA
|
7.5 | IC50 | 2 | — | |
CDCLIURFWZMJLI
|
7.4 | IC50 | 2 | — | |
CFXRLEUFWCPHOC
|
7.4 | Kd | 2 | — | |
FOFVZTDYBUEDIT
|
7.4 | IC50 | 3 | — | |
FRDWFVYYRVMIEO
|
7.4 | IC50 | 3 | — | |
IRGGXYIIIARJBD
|
7.4 | IC50 | 2 | — | |
LHGWWAFKVCIILM
|
7.4 | IC50 | 2 | — | |
BQVOMOZXISVWCA
|
7.4 | IC50 | 2 | — | |
DUXCVYIPXRRATG
|
7.4 | Kd | 2 | — | |
JEHITPSPEWPKHP
|
7.4 | IC50 | 2 | — | |
NXQQYPRJLPVRGW
|
7.4 | IC50 | 2 | — | |
POHJRGFOMQYAJC
|
7.4 | IC50 | 2 | — | |
KOLCMCCJNRJKLN
|
7.4 | IC50 | 2 | — | |
OOPLEVVGBATVMA
|
7.4 | IC50 | 2 | — | |
AXYVGIWCXQOTTL
|
7.4 | IC50 | 2 | — | |
BWYYUEAWOUXJOU
|
7.4 | IC50 | 2 | — | |
CWLPPVPOFQVMLB
|
7.4 | Kd | 2 | — | |
DOWOPJFFGNPYTA
|
7.4 | IC50 | 2 | — | |
HMSPABUZDCZFBN
|
7.4 | Kd | 2 | — | |
KRRWEDJIVLDJJK
|
7.4 | IC50 | 3 | — |