Target Details
| UniProt AC | P07949 |
|---|---|
| Gene Symbol | RET |
| Protein Name | Proto-oncogene tyrosine-protein kinase receptor Ret |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF00028 (Cadherin) PF07714 (PK_Tyr_Ser-Thr) PF17756 (RET_CLD1) PF17812 (RET_CLD3) PF17813 (RET_CLD4) PF22540 (RET_CRD) |
Summary
- Multi-target molecules 656
- Clinical molecules 78
- Avg pChEMBL 7.52
KEGG Pathways (7)
Associated Diseases (6)
Active Molecules (656)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
JVMXFXGOSURYQL
|
10.4 | IC50 | 3 | — | |
UMBIRSZUCJNBHB
|
10.4 | IC50 | 18 | — | |
BAQZVMZHRWELTR
|
10.2 | IC50 | 3 | — | |
WJOMVKXZFSMUMB
|
10.1 | IC50 | 3 | — | |
KBHJOYQXMRWUFC
|
10.0 | IC50 | 3 | — | |
MXBRHEFPFHSZLC
|
10.0 | IC50 | 3 | — | |
QQKGRWXVVZAZJJ
|
10.0 | IC50 | 2 | — | |
ICYGQSKHMTYUQT
|
9.8 | IC50 | 3 | — | |
KFTIUYWZCYZUGD
|
9.8 | IC50 | 3 | — | |
NYCMTZDIVLFLKV
|
9.8 | IC50 | 3 | — | |
ZAAKPRKYIFTIIV
|
9.8 | IC50 | 3 | — | |
ZJVPEIBBMXWONH
|
9.8 | IC50 | 3 | — | |
DFMFALRCABNVBW
|
9.8 | IC50 | 3 | — | |
VKNSWNWSJODLGL
|
9.8 | IC50 | 2 | — | |
SUXYGJZMCWKJJI
|
9.7 | IC50 | 26 | Yes | |
UFKINFUUYHPLQS
|
9.7 | IC50 | 3 | — | |
ZQADJVAMOQTKDB
|
9.7 | IC50 | 3 | — | |
DBSYRDKFSIDUKG
|
9.6 | IC50 | 2 | — | |
OOLMBUKZNOBEOR
|
9.6 | IC50 | 3 | — | |
SOYPGPWJQFUHGG
|
9.6 | IC50 | 3 | — | |
ZGYGQOBLWQGUEB
|
9.6 | IC50 | 2 | — | |
BZUNLTWIUMVYTM
|
9.5 | IC50 | 2 | — | |
YVMCTVCGSKMRCI
|
9.5 | IC50 | 3 | — | |
GBLBJPZSROAGMF
|
9.4 | IC50 | 4 | — | |
ROHJEIACUNTGFP
|
9.4 | IC50 | 16 | — | |
XFVXNAQMQOCOEI
|
9.4 | IC50 | 2 | — | |
QNWAZYDNHYUGCX
|
9.4 | IC50 | 2 | — | |
AHJRPTVABKSPBA
|
9.2 | IC50 | 3 | — | |
CSSQYXSETPQWAY
|
9.2 | IC50 | 2 | — | |
IMBMCIOLXKICJK
|
9.2 | IC50 | 2 | — | |
VCFDMLBPASGZTP
|
9.2 | Ki | 38 | — | |
XCHWBXBDZRJVDP
|
9.2 | Ki | 51 | — | |
ZQKNIPQNEVNCDY
|
9.2 | IC50 | 8 | — | |
GBLBJPZSROAGMF
|
9.2 | IC50 | 3 | — | |
GCDSDVNITVBCDW
|
9.2 | IC50 | 17 | — | |
LEXFJCXUUWNKDZ
|
9.2 | IC50 | 2 | — | |
NCGRGWJXAPPPSD
|
9.2 | IC50 | 2 | — | |
SXIDXVGGABQPIG
|
9.1 | IC50 | 2 | — | |
PHPNGPQLTUCHPN
|
9.1 | IC50 | 2 | — | |
GXEGTVQATHKFDH
|
9.1 | IC50 | 10 | Yes | |
KBMRUKDPKAHAPU
|
9.1 | IC50 | 2 | — | |
MYMBTVRXCNFFNP
|
9.0 | IC50 | 2 | — | |
YEYOIWDLFZJGMH
|
9.0 | IC50 | 2 | — | |
AQSSMEORRLJZLU
|
9.0 | Kd | 34 | Yes | |
AUHQDJKUSKRBFM
|
9.0 | IC50 | 2 | — | |
BRTHUECZMVKNMQ
|
9.0 | Ki | 31 | — | |
CGMQSJXTBXHOTH
|
9.0 | IC50 | 9 | — | |
JFYWOOJDLHFQAP
|
9.0 | IC50 | 2 | — | |
NJLMIILZNLZZFW
|
9.0 | IC50 | 2 | — | |
ORRHVRJUSPCILV
|
9.0 | Ki | 16 | — |