Target Details
| UniProt AC | P07900 |
|---|---|
| Gene Symbol | HSP90AA1 |
| Protein Name | Heat shock protein HSP 90-alpha |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF13589 (HATPase_c_3) PF00183 (HSP90) |
Summary
- Multi-target molecules 674
- Clinical molecules 2
- Avg pChEMBL 7.11
KEGG Pathways (15)
- Antigen processing and presentation
- Chemical carcinogenesis - receptor activation
- Estrogen signaling pathway
- Fluid shear stress and atherosclerosis
- IL-17 signaling pathway
- Lipid and atherosclerosis
- NOD-like receptor signaling pathway
- Necroptosis
- PI3K-Akt signaling pathway
- Pathways in cancer
- Progesterone-mediated oocyte maturation
- Prostate cancer
- Protein processing in endoplasmic reticulum
- Salmonella infection
- Th17 cell differentiation
Active Molecules (674)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
JAXODMFYXRHARC
|
7.0 | IC50 | 2 | — | |
MAVGMAPVSKEVGU
|
7.0 | IC50 | 2 | — | |
FHLSFJTYUGIPLQ
|
7.0 | IC50 | 2 | — | |
LIRXYOSHRDKVEH
|
7.0 | Ki | 2 | — | |
PUZFUDLRFGFPDB
|
7.0 | IC50 | 2 | — | |
ANOUXZUTNMMCOZ
|
7.0 | IC50 | 2 | — | |
VVNCYDUHFFPIAY
|
7.0 | IC50 | 2 | — | |
IKGRZHVFOMUXCQ
|
7.0 | IC50 | 2 | — | |
CKAFUNPJPCPMTQ
|
7.0 | IC50 | 2 | — | |
CVBWTNHDKVVFMI
|
7.0 | IC50 | 2 | — | |
CVBWTNHDKVVFMI
|
7.0 | IC50 | 2 | — | |
FVOWQWQEKSWILA
|
7.0 | IC50 | 13 | — | |
GLYKHSDGYVKDPV
|
7.0 | IC50 | 3 | — | |
IEZBQZOMTACJEB
|
7.0 | IC50 | 2 | — | |
JUOFNVDVYYZOKF
|
7.0 | IC50 | 2 | — | |
KWVNWCSENWQNBZ
|
7.0 | IC50 | 2 | — | |
KYOZHNPREAVXSZ
|
7.0 | IC50 | 2 | — | |
OIYQOJBOWPOPMU
|
7.0 | IC50 | 2 | — | |
QJRZURHQCSFCDN
|
7.0 | IC50 | 13 | — | |
SOAVEOJCKVRROO
|
7.0 | IC50 | 2 | — | |
VALLVLQKXQUOLY
|
7.0 | IC50 | 2 | — | |
VWTYNHIROMEOBP
|
7.0 | Kd | 2 | — | |
XGLORLWBNYUHPT
|
7.0 | IC50 | 2 | — | |
YJZDJCUSZSUGJY
|
7.0 | IC50 | 2 | — | |
YNGUMMOPMXVZSN
|
7.0 | IC50 | 2 | — | |
YNKFGXKCMWZZPR
|
7.0 | IC50 | 2 | — | |
YTDQDZVHCYRHCR
|
7.0 | IC50 | 2 | — | |
ZWVWFCCSBXKBDU
|
7.0 | IC50 | 2 | — | |
QKASCVDKULMPHI
|
7.0 | IC50 | 2 | — | |
ZUEJKPWLTRNAHR
|
7.0 | IC50 | 2 | — | |
KYSAGNXPFPWWSZ
|
7.0 | IC50 | 2 | — | |
MYCBKJICVQNKMP
|
7.0 | IC50 | 2 | — | |
OQJGDSJAPAFPRA
|
7.0 | IC50 | 2 | — | |
PFHGIFRDCPUONW
|
7.0 | IC50 | 3 | — | |
SYSYWMXJRRKVLP
|
7.0 | IC50 | 2 | — | |
VJSOUGMQBHUKBW
|
7.0 | IC50 | 2 | — | |
WCPOBUAEFYTUEO
|
7.0 | IC50 | 2 | — | |
HUJYJAFAOLJFPZ
|
7.0 | IC50 | 2 | — | |
JXHFEOAFQXPYIJ
|
7.0 | IC50 | 5 | — | |
PDTIGQGNOQYHJW
|
7.0 | IC50 | 2 | — | |
PEHIYOQUUMHTNJ
|
7.0 | IC50 | 2 | — | |
QZLDWSFSFMYFDA
|
7.0 | IC50 | 2 | — | |
SOGUPWMOZTZHOM
|
7.0 | IC50 | 2 | — | |
ZIFZVWAUDONUKF
|
7.0 | IC50 | 2 | — | |
DGOVAFNEOBXFEF
|
7.0 | IC50 | 2 | — | |
HCTFLHZOAAGMGI
|
7.0 | IC50 | 2 | — | |
IUIVSQTUTGDTNK
|
7.0 | IC50 | 2 | — | |
KGHRGOKTMYJLCZ
|
7.0 | IC50 | 2 | — | |
SEXLJBIYWSQNIM
|
7.0 | IC50 | 2 | — | |
SPZDKENJERRLBU
|
7.0 | IC50 | 2 | — |