Target Details
| UniProt AC | P07686 |
|---|---|
| Gene Symbol | HEXB |
| Protein Name | Beta-hexosaminidase subunit beta |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF00728 (Glyco_hydro_20) PF14845 (Glycohydro_20b2) |
Summary
- Multi-target molecules 8
- Clinical molecules 0
- Avg pChEMBL 6.48
KEGG Pathways (9)
- Amino sugar and nucleotide sugar metabolism
- Glycosaminoglycan degradation
- Glycosphingolipid biosynthesis - ganglio series
- Glycosphingolipid biosynthesis - globo and isoglobo series
- Lysosome biogenesis
- Metabolic pathways
- Other glycan degradation
- Sphingolipid metabolism
- Various types of N-glycan biosynthesis
Associated Diseases (4)
Active Molecules (8)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
MWKSRKSEWLRPBL
|
7.3 | Kd | 1075 | — | |
RPZPRSQYGSVMTF
|
7.2 | Ki | 2 | — | |
DRHXTSWSUAJOJZ
|
6.6 | Ki | 3 | — | |
GBRAQQUMMCVTAV
|
6.3 | Ki | 2 | — | |
OBBBIYKSFPPMRZ
|
6.2 | Ki | 2 | — | |
WMAYQJQIMIZKFB
|
6.2 | Ki | 2 | — | |
DJQLZCGDQCJIBK
|
6.1 | Ki | 2 | — | |
PWJRCEFNZHHJBF
|
6.0 | Ki | 2 | — |