KLK1 — MultiTargetDB

Target Details

UniProt AC	`P06870`
Gene Symbol	KLK1
Protein Name	Kallikrein-1
Organism	Homo sapiens
Entry Name
Organism Category	Human
Pfam Domains	PF00089 (Trypsin)

Summary

Multi-target molecules 630
Clinical molecules 0
Avg pChEMBL 7.82

KEGG Pathways (2)

Top Co-occurrence Targets

F11 511 shared
F10 39 shared
F2 36 shared
PLAU 33 shared
F3 28 shared
F7 28 shared
PLG 28 shared
KLKB1 27 shared
PRSS1 17 shared
F12 16 shared

Active Molecules (630)

InChIKey	pChEMBL	Type	Targets	Clinical
`VFSABNHMZHTMLQ`	7.3	IC50	2	—
`MJZIQSWEDKVVGO`	7.3	IC50	2	—
`CZRSUKWCMUIVJO`	7.3	Ki	3	—
`IBKXBQSSPQREIN`	7.3	IC50	2	—
`SBELTLOXJSZYPH`	7.3	Ki	2	—
`ZAWJXHNKTBGVQA`	7.3	IC50	2	—
`CWYCXQHAJSFQPS`	7.2	Ki	2	—
`INCTYEOVZVJDGU`	7.2	IC50	2	—
`SZDRBNHFVDDBTN`	7.2	IC50	2	—
`ZYEGJCSHSMVJIY`	7.2	IC50	2	—
`KJRICXCAZCXOLO`	7.2	IC50	2	—
`VIJKHRQIXAYOCB`	7.2	IC50	2	—
`MQQYEKZECDAUFN`	7.2	IC50	2	—
`JENOLOFVMYLCBZ`	7.2	IC50	4	—
`ZLUOAFAJSUPHOG`	7.2	Ki	6	—
`ROUCTUKJYUAHKH`	7.2	IC50	2	—
`FVBDKHAIINLDPZ`	7.2	IC50	2	—
`NGJGSGNOKLPQKE`	7.2	IC50	2	—
`VPQMOLLDQLHVKW`	7.2	IC50	2	—
`VQVJDCBFDKAYQH`	7.2	IC50	2	—
`FHNSYXAYBRIELB`	7.2	IC50	2	—
`ONSBFNASIDWXPA`	7.2	Ki	5	—
`PTCHEYWURWFAME`	7.2	Ki	5	—
`HHTBXDSEQPWJOH`	7.2	IC50	2	—
`LECYFAKUPJDUCN`	7.2	IC50	2	—
`VLHZNIDQBGKPGY`	7.1	IC50	2	—
`LLOVWPOTLNTVCL`	7.1	IC50	2	—
`WOJYOHCXQCTJSI`	7.1	Ki	2	—
`MHOQUZPCDSCDEH`	7.1	IC50	2	—
`BMLGENRLCJEYSQ`	7.1	Ki	2	—
`QZBFVWBAHYWYJI`	7.1	IC50	2	—
`VWKDMGIRFQHGHQ`	7.1	Ki	3	—
`YUWLGIZXLRBQBZ`	7.1	IC50	2	—
`DCTOIQJJYTXRLB`	7.1	IC50	2	—
`LRETYOOLUSXELW`	7.1	IC50	2	—
`CARVFESKMXRKLT`	7.0	Ki	2	—
`OZJUPEDZINETTD`	7.0	IC50	2	—
`PRKWITZMBNVLDR`	7.0	IC50	2	—
`WCKISWFDVPNKDC`	7.0	IC50	2	—
`WCKISWFDVPNKDC`	7.0	IC50	2	—
`YNDRQXGXYGJMNC`	7.0	Ki	2	—
`XOZNFJPIYVLVTF`	7.0	IC50	2	—
`YZNRBKWDIOXEAU`	7.0	IC50	2	—
`DVTJAXWYFLZLAI`	7.0	Ki	3	—
`JENOLOFVMYLCBZ`	7.0	IC50	3	—
`JODGCVISYXBBJZ`	7.0	Ki	3	—
`MMMVHDBARFPCLX`	7.0	Ki	6	—
`WZPQELXAUSQFQX`	7.0	Ki	3	—
`YLOURKKYJRCESD`	7.0	Ki	5	—
`NXUCHCCAARWIAL`	7.0	IC50	2	—