Target Details
| UniProt AC | P06612 |
|---|---|
| Gene Symbol | topA |
| Protein Name | DNA topoisomerase 1 |
| Organism | Escherichia coli (strain K12) |
| Entry Name | |
| Organism Category | Pathogen |
| Pfam Domains | PF01131 (Topoisom_bac) PF01751 (Toprim) PF21372 (Zn_ribbon_bTOP1) PF01396 (Zn_ribbon_Top1) PF08272 (Zn_Ribbon_Topo) |
Summary
- Multi-target molecules 1
- Clinical molecules 0
- Avg pChEMBL 6.14
Top Co-occurrence Targets
- TOP2A 1 shared
Active Molecules (1)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
VQQUXURSDIAWIJ
|
6.1 | IC50 | 2 | — |