Target Details
| UniProt AC | P05362 |
|---|---|
| Gene Symbol | ICAM1 |
| Protein Name | Intercellular adhesion molecule 1 |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF21146 (ICAM1_3_5_D2) PF03921 (ICAM_N) PF13895 (Ig_2) |
Summary
- Multi-target molecules 462
- Clinical molecules 0
- Avg pChEMBL 7.16
KEGG Pathways (19)
- AGE-RAGE signaling pathway in diabetic complications
- African trypanosomiasis
- Cell adhesion molecule (CAM) interaction
- Epstein-Barr virus infection
- Fluid shear stress and atherosclerosis
- Human T-cell leukemia virus 1 infection
- IgSF CAM signaling
- Influenza A
- Integrin signaling
- Kaposi sarcoma-associated herpesvirus infection
- Leukocyte transendothelial migration
- Lipid and atherosclerosis
- Malaria
- NF-kappa B signaling pathway
- Natural killer cell mediated cytotoxicity
- Rheumatoid arthritis
- Staphylococcus aureus infection
- TNF signaling pathway
- Viral myocarditis
Associated Diseases (2)
Active Molecules (462)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
FDHIKTFGAVFLBW
|
6.0 | IC50 | 3 | — | |
PIDWOXMITGALID
|
6.0 | IC50 | 3 | — | |
QZDQYAWTHQIABF
|
6.0 | Kd | 3 | — | |
WCGMRWQSWALRBY
|
6.0 | IC50 | 3 | — | |
KRXBQXJYEYDJNX
|
6.0 | IC50 | 3 | — | |
ASZRMFOYZFBVKS
|
6.0 | IC50 | 3 | — | |
HHRSUWNKIITCSR
|
6.0 | IC50 | 3 | — | |
ODBJFDPUTWIUAM
|
6.0 | IC50 | 3 | — | |
KVFXBGFHMNALFK
|
6.0 | IC50 | 3 | — | |
IOBIQCAVWCTRDY
|
6.0 | IC50 | 3 | — | |
QHTCEKBPRLPPSG
|
6.0 | IC50 | 3 | — | |
YLBZKNBFLLAXRX
|
6.0 | IC50 | 3 | — |