Target Details
| UniProt AC | P04899 |
|---|---|
| Gene Symbol | GNAI2 |
| Protein Name | Guanine nucleotide-binding protein G(i) subunit alpha-2 |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF00503 (G-alpha) |
Summary
- Multi-target molecules 3
- Clinical molecules 1
- Avg pChEMBL 6.73
KEGG Pathways (43)
- Adrenergic signaling in cardiomyocytes
- Alcoholism
- Apelin signaling pathway
- Axon guidance
- Chagas disease
- Chemical carcinogenesis - receptor activation
- Chemokine signaling pathway
- Cholinergic synapse
- Circadian entrainment
- Cocaine addiction
- Cushing syndrome
- Dopaminergic synapse
- Estrogen signaling pathway
- GABAergic synapse
- Gap junction
- Gastric acid secretion
- Glutamatergic synapse
- Growth hormone synthesis, secretion and action
- Hormone signaling
- Human cytomegalovirus infection
- Human immunodeficiency virus 1 infection
- Leukocyte transendothelial migration
- Long-term depression
- Melanogenesis
- Morphine addiction
- Neuroactive ligand signaling
- Oxytocin signaling pathway
- Parathyroid hormone synthesis, secretion and action
- Parkinson disease
- Pathways in cancer
- Pertussis
- Platelet activation
- Progesterone-mediated oocyte maturation
- Rap1 signaling pathway
- Regulation of lipolysis in adipocytes
- Relaxin signaling pathway
- Renin secretion
- Retrograde endocannabinoid signaling
- Serotonergic synapse
- Sphingolipid signaling pathway
- Toxoplasmosis
- cAMP signaling pathway
- cGMP-PKG signaling pathway
Associated Diseases (2)
Active Molecules (3)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
MWKSRKSEWLRPBL
|
6.9 | Kd | 1075 | — | |
ZLHFILGSQDJULK
|
6.7 | Kd | 37 | Yes | |
ZCCPLJOKGAACRT
|
6.5 | Kd | 599 | — |