Target Details
| UniProt AC | P04439 |
|---|---|
| Gene Symbol | HLA-A |
| Protein Name | HLA class I histocompatibility antigen, A alpha chain |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF07654 (C1-set) PF00129 (MHC_I) PF06623 (MHC_I_C) |
Summary
- Multi-target molecules 1
- Clinical molecules 0
- Avg pChEMBL 7.26
KEGG Pathways (19)
- Allograft rejection
- Antigen processing and presentation
- Autoimmune thyroid disease
- Cell adhesion molecule (CAM) interaction
- Cellular senescence
- Endocytosis
- Epstein-Barr virus infection
- Graft-versus-host disease
- Herpes simplex virus 1 infection
- Human T-cell leukemia virus 1 infection
- Human cytomegalovirus infection
- Human immunodeficiency virus 1 infection
- Human papillomavirus infection
- Kaposi sarcoma-associated herpesvirus infection
- Natural killer cell mediated cytotoxicity
- Phagosome
- Type I diabetes mellitus
- Viral carcinogenesis
- Viral myocarditis
Associated Diseases (1)
Active Molecules (1)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
MWKSRKSEWLRPBL
|
7.3 | Kd | 1075 | — |