Target Details
UniProt ACP03956
Gene SymbolMMP1
Protein NameInterstitial collagenase
OrganismHomo sapiens
Entry Name
Organism Category Human
Pfam Domains PF00045 (Hemopexin) PF00413 (Peptidase_M10) PF01471 (PG_binding_1)
UniProt
Summary
  • Multi-target molecules 1,338
  • Clinical molecules 1178
  • Avg pChEMBL 7.11
KEGG Pathways (8)
Associated Diseases (2)
Top Co-occurrence Targets
Active Molecules (1,338)
InChIKey pChEMBL Type Targets Clinical
SJPBXYWXFIQQJH 7.8 Ki 5 Yes
KJBQTISDZZFFDE 7.8 IC50 5 Yes
PNOYLKIRWUYKLC 7.8 IC50 4 —
RGDBGIBFYROBCD 7.8 Ki 5 Yes
SFESNYSPTLYJFZ 7.8 IC50 6 Yes
VDJRMQXPNKTLQA 7.8 IC50 5 Yes
HVHBPSLGXXXKOR 7.8 Ki 7 Yes
NJSAPXUDAYVTFL 7.8 Ki 7 Yes
RLVHPDACJUGNSL 7.8 Ki 6 Yes
XUDSOJRUANECGX 7.8 Ki 5 Yes
CBKKHHSQVZVIBM 7.7 IC50 6 Yes
HHSADBHNZPOTTJ 7.7 Ki 7 Yes
HXZPYZWICHZKRL 7.7 IC50 10 —
IGWLPPHUCLZWTC 7.7 Ki 5 Yes
IHERVMJHCHNTKO 7.7 IC50 7 Yes
JDOCJRYXQAWUOO 7.7 IC50 7 Yes
JGHZXBJPZQXVAB 7.7 IC50 6 Yes
KJVHFBOUABDIQV 7.7 IC50 5 Yes
OOCSYABQMHKMLM 7.7 IC50 6 Yes
PCQHVURJJBFBQG 7.7 Ki 7 Yes
QUEIBYWBRFSDLX 7.7 IC50 6 Yes
HFCXLBPJFPHTAN 7.7 Ki 7 Yes
BSGLIFPGYIIUAJ 7.7 IC50 7 Yes
IPBUPOIKMNEPGS 7.7 IC50 5 Yes
ITNSNSYBFZWVPE 7.7 IC50 5 Yes
IZXHKSIJYAXOFC 7.7 IC50 5 Yes
MTGNBEKVSCTMSE 7.7 IC50 5 Yes
NOXYNXIAEWTFQX 7.7 IC50 7 Yes
NUDMVYOFBGJGMN 7.7 IC50 5 Yes
SMZPWUUYPYYHIV 7.7 IC50 5 Yes
TZQQXIZDSZWWPC 7.7 IC50 6 Yes
HIWQTXDWQYKMGH 7.7 Ki 7 Yes
ARFFCGXUOISSHZ 7.7 IC50 6 Yes
CNVCLEPNZAFTKK 7.7 IC50 5 Yes
HSJPSXSXQYYJSY 7.7 Ki 7 Yes
IIDUBAKXXSWORH 7.7 IC50 5 Yes
LXKHXLQQHKRMFP 7.7 Ki 7 Yes
MMOBDSFVSOBMOV 7.7 IC50 7 Yes
NFRICHJLQIOONF 7.7 IC50 6 Yes
OAXIYDWDKICQCU 7.7 IC50 6 Yes
OPPSVVRCTWTXLK 7.7 IC50 5 Yes
UBFGIEDUTRCMEQ 7.7 IC50 3 —
ULPVLGUDYQAPPV 7.7 Ki 7 Yes
UUKHUELBYRLVFI 7.7 IC50 2 —
VCKCQHDSLLCTDH 7.7 IC50 6 Yes
WXUQPWYPRTYWIR 7.7 IC50 6 Yes
YRUNEWMUGNJMAR 7.7 Ki 7 Yes
DMOIDCGAIGWXGJ 7.7 Ki 7 Yes
DWFUVVZGNJNHKO 7.7 Ki 7 Yes
DZZFIOQATPLRLB 7.7 Ki 4 Yes
2D structure