Target Details
UniProt ACP03372
Gene SymbolESR1
Protein NameEstrogen receptor
OrganismHomo sapiens
Entry Name
Organism Category Human
Pfam Domains PF12743 (ESR1_C) PF00104 (Hormone_recep) PF02159 (Oest_recep) PF00105 (zf-C4)
UniProt
Summary
  • Multi-target molecules 1,446
  • Clinical molecules 982
  • Avg pChEMBL 7.47
KEGG Pathways (10)
Associated Diseases (3)
Top Co-occurrence Targets
Active Molecules (1,446)
InChIKey pChEMBL Type Targets Clinical
JAVIIUAYGNOEAR 9.3 IC50 4 Yes
JGIGPQNAVZRGNQ 9.3 IC50 4 Yes
KRKRBIVNILCKBI 9.3 IC50 4 Yes
PJDIJYZHMSPAKC 9.3 IC50 4 Yes
SZCIUMNCRFCHKW 9.3 IC50 4 Yes
UOZGUWHPVZIRDP 9.3 IC50 4 Yes
NJVFOFMHUJJIMB 9.3 Ki 4 Yes
IKZMTNSYXDOFJH 9.3 IC50 4 Yes
KZGJWJJJDKPFMH 9.2 Ki 4 Yes
DMJJJIYHTDJNMV 9.2 IC50 2 —
ISNMOIVTZCAIGR 9.2 IC50 4 Yes
KNKMMFVVMHOSMW 9.2 IC50 4 Yes
MBLXCRLKWJLKIM 9.2 IC50 4 Yes
NITXIOJXVVTKIJ 9.2 IC50 4 Yes
NITXIOJXVVTKIJ 9.2 IC50 2 —
SNURMSXWIAIOCJ 9.2 IC50 4 Yes
VKHAZLNFXPDJLK 9.2 IC50 4 Yes
XKPFIOPKBVZILS 9.2 IC50 4 Yes
WLEXCTJQABXUGS 9.2 IC50 4 Yes
AKRKKOYYGGSJRD 9.2 IC50 4 Yes
QZFNCDFOOSETTB 9.2 IC50 4 Yes
DIKAQBJCHZVUSN 9.2 IC50 2 —
YVWMSUSLLTXXJV 9.2 Ki 4 Yes
ZMANQSXBZZYBCV 9.2 IC50 2 —
COJFASLRENZFLP 9.2 IC50 4 Yes
GTPUHNJIMQQEMY 9.2 IC50 4 Yes
IQWWKHVNEDNTHC 9.2 IC50 4 Yes
KRKRBIVNILCKBI 9.2 IC50 4 Yes
LXPJFKHIHBCXNT 9.2 IC50 4 Yes
OYAILXOXIFBWFX 9.2 IC50 4 Yes
QLYZYLKQDKMAOV 9.2 IC50 2 —
SGZMYPDLACFIAW 9.2 IC50 4 Yes
UOZGUWHPVZIRDP 9.2 IC50 4 Yes
WLGDFYOOSGHIPS 9.2 IC50 4 Yes
ZTMDXFVSRFQNLX 9.2 IC50 4 Yes
NMXUKCANMSBQDR 9.1 Ki 4 Yes
ZOIOYCAFYGHCOY 9.1 IC50 2 —
CRLVKJCAHBZLJT 9.1 IC50 4 Yes
DFHBLNUDXVTIIS 9.1 IC50 2 —
KOYRLVBQHJNLQX 9.1 IC50 4 Yes
KREZVKKCLKOMEF 9.1 IC50 4 Yes
KREZVKKCLKOMEF 9.1 IC50 4 Yes
LCRLCVCOQDLILD 9.1 IC50 4 Yes
NWKCPPJDKLUHDY 9.1 IC50 4 Yes
TWZNCTCQAGRUGQ 9.1 IC50 4 Yes
UPNAHMSJUMHPOR 9.1 IC50 4 Yes
WLGDFYOOSGHIPS 9.1 IC50 4 Yes
RDIWNJDCZLGDOS 9.1 IC50 2 —
QQVLWSVTWRIXTG 9.1 IC50 4 Yes
AHZXOWRUYBWOSI 9.1 IC50 4 Yes
2D structure