Target Details
UniProt ACP03372
Gene SymbolESR1
Protein NameEstrogen receptor
OrganismHomo sapiens
Entry Name
Organism Category Human
Pfam Domains PF12743 (ESR1_C) PF00104 (Hormone_recep) PF02159 (Oest_recep) PF00105 (zf-C4)
UniProt
Summary
  • Multi-target molecules 1,446
  • Clinical molecules 982
  • Avg pChEMBL 7.47
KEGG Pathways (10)
Associated Diseases (3)
Top Co-occurrence Targets
Active Molecules (1,446)
InChIKey pChEMBL Type Targets Clinical
JKCIXMFRPFCAET 10.2 Ki 2 —
DUYNJNWVGIWJRI 10.1 Ki 4 Yes
DUYNJNWVGIWJRI 10.1 IC50 4 Yes
KJAAPZIFCQQQKX 10.1 IC50 2 —
LSMUQPOCAXNDRJ 10.0 Ki 4 Yes
MLBZDTAIIVFHLO 9.8 Ki 2 —
XSIHFOOFJWBVHK 9.8 Ki 4 Yes
ZPECPOOQJUIDLY 9.7 Ki 4 Yes
KPQNZYYSEZBIEF 9.7 IC50 2 —
RCVOOQFPOXBKPQ 9.7 Ki 4 Yes
SSQLMQBZAPRIRS 9.7 IC50 4 Yes
UQRWUYACRDDBAE 9.7 IC50 2 —
UQRWUYACRDDBAE 9.7 IC50 4 Yes
RIUHJWNFKOJLRS 9.7 Ki 4 Yes
CXNZLOIPQFMHLT 9.7 IC50 4 Yes
JHTAVPGZAPVPGG 9.7 IC50 4 Yes
BFPYWIDHMRZLRN 9.6 Ki 2 —
ZPPXQVFYCAJAFB 9.6 Ki 4 Yes
CGNLKIUQLVMBMO 9.6 Ki 4 Yes
JMSHBDSUSOGKTP 9.6 Ki 4 Yes
SISSMRYZIKZMPG 9.6 IC50 2 —
YLXJVLPPXCTXSA 9.6 IC50 4 Yes
LQEOPHGPHCWOAC 9.6 IC50 4 Yes
WDHIYKZHKBKYCY 9.6 Ki 4 Yes
BGIIEAJTIOAKIR 9.5 IC50 4 Yes
JUMHXAHUWIPRTK 9.5 IC50 4 Yes
SXNATFXZAWSPSE 9.5 IC50 4 Yes
YMMHAHMATMOTRF 9.5 IC50 4 Yes
LXRGAVBXYQAUEY 9.5 Ki 4 Yes
RVTQUEREFMHYHS 9.5 IC50 2 —
FSYFYSFYUHBIHE 9.5 Ki 2 —
FSYFYSFYUHBIHE 9.5 Ki 4 Yes
SMYDPKRFVHAWET 9.4 Ki 4 Yes
PATAFNKRVMWVGP 9.4 IC50 2 —
COJFASLRENZFLP 9.4 IC50 4 Yes
RGLYKWWBQGJZGM 9.4 IC50 8 Yes
TZFOGJYLHDBPIJ 9.4 IC50 4 Yes
UXVJUMKPIQCRPX 9.4 IC50 4 Yes
WGUNFTKBYUCLEL 9.4 Ki 4 Yes
YMMHAHMATMOTRF 9.4 IC50 4 Yes
QYZVZGPAIPNEDN 9.4 IC50 4 Yes
OEKMGABCSLYWOP 9.4 Ki 4 Yes
BDKWTFFBJKKPEK 9.3 IC50 4 Yes
CIMWNILMBKPFET 9.3 Ki 2 —
QCTHZNDHZKAUOH 9.3 Ki 4 Yes
QQOLSZOGLJIRPW 9.3 Ki 4 Yes
COJFASLRENZFLP 9.3 IC50 4 Yes
DAENOLUGFUWJQG 9.3 IC50 2 —
GXESHMAMLJKROZ 9.3 IC50 2 —
ISNMOIVTZCAIGR 9.3 IC50 4 Yes
2D structure