Target Details
UniProt ACP03367
Gene Symbolgag-pol
Protein NameGag-Pol polyprotein
OrganismHuman immunodeficiency virus type 1 group M subtype B (isolate BRU/LAI)
Entry Name
Organism Category Pathogen
Pfam Domains PF00540 (Gag_p17) PF19317 (Gag_p24_C) PF00552 (IN_DBD_C) PF02022 (Integrase_Zn) PF00075 (RNase_H) PF00665 (rve) PF00077 (RVP) PF00078 (RVT_1) PF06815 (RVT_connect) PF06817 (RVT_thumb) PF00098 (zf-CCHC)
Summary
  • Multi-target molecules 310
  • Clinical molecules 0
  • Avg pChEMBL 8.44
Top Co-occurrence Targets
Active Molecules (310)
InChIKey pChEMBL Type Targets Clinical
UXBUYQULNOSYKV 6.5 Ki 2
VFXWXTTYUYUQCX 6.5 Ki 2
CFFYNIWNUKREJO 6.5 Ki 2
RBHLYDAZGYDJGN 6.3 Ki 2
HSHYCDVIHVMARS 6.3 Ki 2
UNKRIVFTEBBFTP 6.2 Ki 2
LZQOFODQYKDVGM 6.1 IC50 2
MFPWTYXTECUSIK 6.1 Ki 2
BMXYVKCLBAGXOY 6.0 Ki 2
IOCNYGPHBFUDJN 6.0 Ki 2
2D structure