Target Details
UniProt ACP03366
Gene Symbolgag-pol
Protein NameGag-Pol polyprotein
OrganismHuman immunodeficiency virus type 1 group M subtype B (isolate BH10)
Entry Name
Organism Category Pathogen
Pfam Domains PF00540 (Gag_p17) PF19317 (Gag_p24_C) PF00552 (IN_DBD_C) PF02022 (Integrase_Zn) PF00075 (RNase_H) PF00665 (rve) PF00077 (RVP) PF00078 (RVT_1) PF06815 (RVT_connect) PF06817 (RVT_thumb) PF00098 (zf-CCHC)
UniProt
Summary
  • Multi-target molecules 580
  • Clinical molecules 0
  • Avg pChEMBL 7.7
Top Co-occurrence Targets
Active Molecules (580)
InChIKey pChEMBL Type Targets Clinical
QCPLFLMUPQQDHG 8.5 IC50 2 —
QNKGCZRNGSRJSA 8.5 IC50 2 —
RRXROQFWNTVHET 8.5 IC50 2 —
UQPONNCPUBDKTN 8.5 IC50 2 —
VRDRMAIJYVOHHM 8.5 IC50 2 —
WRLDPBMJKRENNH 8.5 IC50 2 —
FNDMBAHDRWSMJJ 8.5 IC50 2 —
FRVMXOZKBATZHP 8.5 IC50 2 —
PYORNCITQOHDMO 8.5 IC50 2 —
UUPLSKTVTNROPX 8.5 IC50 2 —
WEJHEDBFTVRYIQ 8.5 IC50 2 —
YOUMQFHCKGVIOK 8.5 IC50 2 —
BVIKUKOEBQSWCP 8.5 IC50 2 —
DJZJPFSVPYEXNR 8.5 IC50 2 —
HOUHSPMYAXWVED 8.5 IC50 2 —
KJAWMEPCXOAXKA 8.5 IC50 2 —
NOJWSHDYTCQYMI 8.5 IC50 2 —
ORCGZGMYLSXBBM 8.5 IC50 2 —
RNSPJBFCXZWMNP 8.5 IC50 2 —
UUGSZQNVCBJBKQ 8.5 IC50 2 —
VJYMVLARZIYXFF 8.5 IC50 2 —
WBPDGVADTLBPFH 8.5 IC50 2 —
WSOWFARQJAFMNX 8.5 IC50 2 —
YRJUUGOXNJTWQU 8.5 IC50 2 —
BLOROOYSUICZAV 8.5 IC50 2 —
CZUDPIAYZYIGQU 8.5 IC50 2 —
DVTZFWXVVAJVOU 8.5 IC50 2 —
JQRUAXYKOKRDTL 8.5 IC50 2 —
NCGSRAFPARBOND 8.5 IC50 2 —
PEDYRRJAQADMEG 8.5 IC50 2 —
SZDGDGXIKGROIB 8.5 IC50 2 —
CRRBOEIFXMRQHA 8.4 IC50 2 —
FFQAJSHQPAQCOJ 8.4 IC50 2 —
VWBCONAHLFKQEK 8.4 IC50 2 —
WCBVEKBAQGHHMM 8.4 IC50 2 —
WOWIDUSMKYGEKX 8.4 IC50 2 —
HMVNJFZCZQWXIK 8.4 IC50 2 —
ICEOCJMVQJBPGI 8.4 IC50 2 —
NYIGQHHAXOELKN 8.4 IC50 2 —
PSMDDWGSPKKKTR 8.4 IC50 2 —
QPCZVNUHZVGVRP 8.4 IC50 2 —
WPNFTZUZKDERHX 8.4 IC50 2 —
SRZALQJMWXNPDC 8.4 IC50 2 —
UIFFADDBFQIHPB 8.4 IC50 2 —
FCPRHCUNXAVUFM 8.4 IC50 2 —
FNDMBAHDRWSMJJ 8.4 IC50 2 —
SJTHHIDTKARDFX 8.4 IC50 2 —
UVFXOSXTUAZJKS 8.4 IC50 2 —
RRQHNLLRIDZOIZ 8.4 IC50 2 —
RWEPHRWVICNXFN 8.4 IC50 2 —
2D structure