Target Details
UniProt ACP02766
Gene SymbolTTR
Protein NameTransthyretin
OrganismHomo sapiens
Entry Name
Organism Category Human
Pfam Domains PF00576 (Transthyretin)
UniProt
Summary
  • Multi-target molecules 125
  • Clinical molecules 4
  • Avg pChEMBL 7.33
KEGG Pathways (1)
Associated Diseases (3)
Top Co-occurrence Targets
Active Molecules (125)
InChIKey pChEMBL Type Targets Clinical
JABDGKTYXKTOFM 7.5 IC50 2 —
BUTDCAJURAHJIA 7.5 IC50 2 —
CHKZQKZXKVDNGY 7.5 IC50 2 —
ATUWTLTWUJDGJA 7.5 IC50 2 —
IYOICLOOPHWRQQ 7.5 IC50 2 —
LPEPZBJOKDYZAD 7.5 Kd 7 —
KKDYSKBDZBOVNK 7.5 IC50 2 —
BKDCWIRSLJFLBQ 7.5 IC50 2 —
XQDWHCGDXCNVJZ 7.5 IC50 2 —
WHXXHQYOLJDQTC 7.5 IC50 2 —
GUCHXVVEHJYGON 7.5 IC50 2 —
VQGIKVKNRWRQES 7.5 IC50 2 —
ICLMEKJUQKPSNH 7.4 IC50 2 —
PQVZRIZWARODSS 7.4 IC50 2 —
ZKCICMGTYICZNJ 7.4 IC50 2 —
QGWDQLGWGRBSSY 7.4 IC50 2 —
XTUGNIIYTUUSNG 7.4 IC50 2 —
MDVPYPGYICUVIX 7.4 IC50 2 —
NGTQEUNANAMCJQ 7.4 IC50 2 —
UMQQOGIDEJUVRL 7.4 IC50 2 —
HHIPLGZKKZDKRY 7.4 IC50 2 —
UTIAPHQXHGWUPS 7.4 IC50 2 —
YHHHPDPWTNQOQT 7.4 IC50 2 —
BYLLNMKTVBNQAZ 7.4 IC50 2 —
ZYVALIUKYONGRR 7.4 IC50 2 —
UJAREHQZMQBEQI 7.3 IC50 2 —
WCFKZDUVRSHWNK 7.3 IC50 2 —
YRCAQAOKTBSUDR 7.3 IC50 2 —
FRWALVZJMIUXEI 7.3 IC50 2 —
KNGWZGVXZMUOFH 7.3 IC50 2 —
OIOXFKNTAAPPQB 7.3 IC50 2 —
YDANNECKGDGCPS 7.3 IC50 2 —
YKBRLQAQNFGOMR 7.3 IC50 2 —
CGVWPYJITSJFDR 7.3 IC50 2 —
JIUAJRLDGAKETK 7.3 IC50 2 —
RKXFRRIIBPDSGE 7.2 IC50 2 —
WLJYUHGFHJXGIS 7.2 IC50 2 —
IOKNVRXRYZUMMP 7.2 IC50 2 —
JFIOVJDNOJYLKP 7.2 Kd 12 Yes
DZHQXNQMYLPSNP 7.2 IC50 2 —
PBSYODFPTYEGSS 7.2 IC50 2 —
YNXUQGHIKVMXOA 7.2 IC50 2 —
SXKMKSSYTXTXTN 7.2 IC50 2 —
HFILSHALEDINDT 7.1 IC50 2 —
JJWWZBIYALJWLH 7.1 IC50 2 —
KJUBEUGLOQFCSV 7.1 IC50 2 —
NRFZKVVDOMMYNN 7.1 IC50 2 —
ZTMVVXVNUYFRJG 7.1 IC50 2 —
PBOABBZHNNGSBL 7.1 IC50 2 —
PJUXIWWOLCCJBG 7.1 IC50 2 —
2D structure