Target Details
| UniProt AC | P02766 |
|---|---|
| Gene Symbol | TTR |
| Protein Name | Transthyretin |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF00576 (Transthyretin) |
Summary
- Multi-target molecules 125
- Clinical molecules 4
- Avg pChEMBL 7.33
KEGG Pathways (1)
Associated Diseases (3)
Active Molecules (125)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
WYOYZAUCDDVZCO
|
8.2 | IC50 | 2 | — | |
DOJQDLFPWKCNSN
|
8.1 | IC50 | 2 | — | |
QUCUJWIXXDENAJ
|
8.0 | IC50 | 2 | — | |
DLBXZUYYANTONO
|
8.0 | IC50 | 2 | — | |
XPZSJBRIZGQERI
|
8.0 | IC50 | 2 | — | |
RKUQJHKAGGHWJC
|
8.0 | IC50 | 2 | — | |
VGWBIQACZZJMGX
|
7.9 | IC50 | 2 | — | |
PWIGKBBQUQWEQM
|
7.9 | IC50 | 2 | — | |
TZIIUZZREBUIBM
|
7.9 | IC50 | 3 | — | |
CTUOVDKHQQRVDA
|
7.8 | IC50 | 2 | — | |
HNDGQBMTGVMHKA
|
7.8 | IC50 | 2 | — | |
DKKZZDVJQMFYCP
|
7.8 | IC50 | 2 | — | |
IFFMFTYOPFDBFM
|
7.8 | IC50 | 2 | — | |
HAGSLCBZFRRBLS
|
7.8 | IC50 | 2 | — | |
GMPSCGGNUUCRKH
|
7.8 | IC50 | 2 | — | |
JVJPYPWJFBHHTF
|
7.8 | IC50 | 2 | — | |
VICXOPXLVAUSNR
|
7.8 | IC50 | 2 | — | |
GJTXRBIAOKTGFT
|
7.8 | IC50 | 2 | — | |
YTTASUWVZYIHOL
|
7.7 | IC50 | 2 | — | |
ACXBVSKTSMMJDB
|
7.7 | IC50 | 2 | — | |
MWEFRQGRHHPSMX
|
7.7 | IC50 | 2 | — | |
XEPOCPGPNGGIJI
|
7.7 | IC50 | 2 | — | |
HNGOJYLRHLPAME
|
7.7 | IC50 | 2 | — | |
FGGJPCWPWDFBRD
|
7.7 | IC50 | 2 | — | |
TXJTYIKCTGYLBH
|
7.7 | IC50 | 2 | — | |
ULZQGRBUAQDIBD
|
7.7 | IC50 | 2 | — | |
AUBAPOMVEQJTIV
|
7.7 | IC50 | 2 | — | |
ICVLYVUETZMGBM
|
7.7 | IC50 | 2 | — | |
LXRKRDSCUQHHSE
|
7.7 | IC50 | 2 | — | |
HKZWDDGISFFTQJ
|
7.7 | IC50 | 2 | — | |
MBYQLRKMIKVLIC
|
7.6 | IC50 | 2 | — | |
SPDWHMKMMHZFBZ
|
7.6 | IC50 | 2 | — | |
UZSKQBUZGPQZTH
|
7.6 | IC50 | 2 | — | |
XAOAHPTWAZHDLT
|
7.6 | IC50 | 2 | — | |
XYEQGCJBSSQRNJ
|
7.6 | IC50 | 2 | — | |
ASNPHZPNQFLZDK
|
7.6 | IC50 | 2 | — | |
KCXAZAZQUSVGRE
|
7.6 | IC50 | 2 | — | |
LSPYBHFCMUSKOR
|
7.6 | IC50 | 2 | — | |
PPCCAKJVNYVYOM
|
7.6 | IC50 | 2 | — | |
MFDDYZMTSXINRF
|
7.6 | IC50 | 2 | — | |
MJPBMNLZJDOKCU
|
7.6 | IC50 | 2 | — | |
LLZJRMIXDPBPBN
|
7.6 | IC50 | 2 | — | |
YOWKPWSHXYIUJQ
|
7.6 | IC50 | 2 | — | |
KHMBUOYZJMXWCD
|
7.6 | IC50 | 2 | — | |
BQJVVKXSYPWHHR
|
7.6 | IC50 | 2 | — | |
FGVUZNOLOHNSHL
|
7.6 | IC50 | 2 | — | |
GPDRPMWKBMJMGR
|
7.6 | IC50 | 2 | — | |
PAMFAASCPAXMJA
|
7.6 | IC50 | 2 | — | |
VUOHHRCTQZELNM
|
7.6 | IC50 | 2 | — | |
YKDMHXXHTRTRAT
|
7.6 | IC50 | 2 | — |