Target Details
| UniProt AC | P02751 |
|---|---|
| Gene Symbol | FN1 |
| Protein Name | Fibronectin |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF00039 (fn1) PF00040 (fn2) PF00041 (fn3) |
Summary
- Multi-target molecules 3
- Clinical molecules 3
- Avg pChEMBL 7.5
KEGG Pathways (14)
- AGE-RAGE signaling pathway in diabetic complications
- Amoebiasis
- Bacterial invasion of epithelial cells
- Cytoskeleton in muscle cells
- ECM-receptor interaction
- Focal adhesion
- Human papillomavirus infection
- Integrin signaling
- PI3K-Akt signaling pathway
- Pathways in cancer
- Proteoglycans in cancer
- Regulation of actin cytoskeleton
- Small cell lung cancer
- Yersinia infection
Associated Diseases (2)
Active Molecules (3)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
RFSFIDGEFVXSQM
|
8.0 | IC50 | 12 | Yes | |
IWGIXRMJMSKLGP
|
7.8 | IC50 | 4 | Yes | |
RONIOIPFUMELRH
|
6.7 | IC50 | 4 | Yes |