Target Details
| UniProt AC | P02708 |
|---|---|
| Gene Symbol | CHRNA1 |
| Protein Name | Acetylcholine receptor subunit alpha |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF02931 (Neur_chan_LBD) PF02932 (Neur_chan_memb) |
Summary
- Multi-target molecules 50
- Clinical molecules 0
- Avg pChEMBL 7.21
KEGG Pathways (2)
Associated Diseases (2)
Active Molecules (50)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
VBQDZZHUUPHQGQ
|
8.8 | IC50 | 11 | — | |
PREYWAJYVTVVPE
|
8.7 | IC50 | 10 | — | |
JYBXLCIZWPNCMU
|
8.6 | IC50 | 11 | — | |
PGTPXIBBHIHMQS
|
8.4 | IC50 | 10 | — | |
ABPSWEJOHYDZDP
|
8.2 | IC50 | 11 | — | |
VLLKJTHFWNJPCE
|
8.2 | IC50 | 9 | — | |
ZZWUEOYQVWAKCJ
|
8.2 | IC50 | 9 | — | |
QYLKSFXBRALDIS
|
8.1 | IC50 | 9 | — | |
ZMRXSORFBXMBCB
|
8.0 | IC50 | 8 | — | |
MXUDEADPGZWZCH
|
8.0 | IC50 | 9 | — | |
GIDJZDYNVHMFAH
|
8.0 | IC50 | 9 | — | |
YDGOUEKZXBLUDG
|
8.0 | IC50 | 8 | — | |
BMWDQBTXNBGORC
|
7.9 | IC50 | 8 | — | |
PFEJBPNFLAFPKN
|
7.9 | IC50 | 10 | — | |
IELBAACIVCODPI
|
7.8 | IC50 | 8 | — | |
BJLKZFUZNNATGZ
|
7.8 | IC50 | 7 | — | |
DGQVZUDAKWRJPY
|
7.8 | IC50 | 8 | — | |
SYMAJWVHHBJSJV
|
7.8 | IC50 | 8 | — | |
ZKFFJBXJJFDBJM
|
7.8 | IC50 | 8 | — | |
AMOKJMKEFDPTPN
|
7.7 | IC50 | 7 | — | |
DNVMLFGJFSQQDE
|
7.7 | IC50 | 9 | — | |
JRPWUGPYWRJACU
|
7.6 | IC50 | 8 | — | |
CFVHNYYHCCJXDK
|
7.6 | IC50 | 9 | — | |
LOWDJVQAZMFOLZ
|
7.5 | IC50 | 10 | — | |
CCGVLNAUEKVICK
|
7.5 | IC50 | 8 | — | |
DDDMGCMKOCLAAT
|
7.4 | IC50 | 8 | — | |
VMEDIUSDIYRUSA
|
7.3 | IC50 | 10 | — | |
JBABGZDZOMSKLX
|
7.2 | IC50 | 8 | — | |
VIWKHXNVEIOPSC
|
7.1 | IC50 | 10 | — | |
XFBDKMSGGGCNAI
|
6.9 | IC50 | 11 | — | |
NLPRAJRHRHZCQQ
|
6.8 | IC50 | 7 | — | |
NLPRAJRHRHZCQQ
|
6.8 | IC50 | 7 | — | |
ANJTVLIZGCUXLD
|
6.6 | Ki | 9 | — | |
IMYZQPCYWPFTAG
|
6.5 | IC50 | 8 | — | |
XKFMBGWHHBCWCD
|
6.5 | Ki | 7 | — | |
CXOPDJYVJZLVSY
|
6.3 | Ki | 6 | — | |
LZJKYCFNHCYHCM
|
6.3 | Ki | 8 | — | |
WITLOMKPGROHOE
|
6.2 | Ki | 4 | — | |
LIWBYJGLHCGRCM
|
6.2 | Ki | 8 | — | |
IMYZQPCYWPFTAG
|
6.2 | IC50 | 8 | — | |
ASEWWVGXMJQYTD
|
6.2 | Ki | 8 | — | |
FVYGPOGSXRAZEB
|
6.1 | Ki | 4 | — | |
FQWLGYQDBDGALN
|
6.1 | IC50 | 4 | — | |
RPQHJWKLRRXKIS
|
6.1 | IC50 | 2 | — | |
BKRDDYIAVADMIJ
|
6.1 | Ki | 5 | — | |
LYMBELAAKZROPC
|
6.0 | Ki | 4 | — | |
AJTVQZWUKUPHIP
|
6.0 | IC50 | 3 | — | |
RCCDDPHPJBBTOH
|
6.0 | Ki | 4 | — | |
VHGCDTVCOLNTBX
|
6.0 | Ki | 19 | — | |
ZORLJXWXFABTPZ
|
6.0 | IC50 | 9 | — |