Target Details
| UniProt AC | P02458 |
|---|---|
| Gene Symbol | COL2A1 |
| Protein Name | Collagen alpha-1(II) chain |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF01410 (COLFI) PF01391 (Collagen) PF00093 (VWC) |
Summary
- Multi-target molecules 1
- Clinical molecules 0
- Avg pChEMBL 8.08
KEGG Pathways (6)
Associated Diseases (13)
- Achondrogenesis type II
- Avascular necrosis of femoral head
- Czech dysplasia
- Kniest dysplasia
- Legg-Calve-Perthes Disease
- Multiple epiphyseal dysplasia
- Osteoarthritis with mild chondrodysplasia
- Spondyloepimetaphyseal dysplasia
- Spondyloepiphyseal dysplasia congenita
- Spondylometaphyseal dysplasia
- Stickler syndrome
- Type II collagenopathies
- Vitreoretinal degeneration
Active Molecules (1)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
YDCCHZDGDMSTQT
|
8.1 | IC50 | 5 | — |