Target Details
| UniProt AC | P01730 |
|---|---|
| Gene Symbol | CD4 |
| Protein Name | T-cell surface glycoprotein CD4 |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF05790 (C2-set) PF09191 (CD4-extracel) PF00047 (ig) PF12104 (Tcell_CD4_C) |
Summary
- Multi-target molecules 4
- Clinical molecules 0
- Avg pChEMBL 7.32
KEGG Pathways (14)
- Antigen processing and presentation
- Cell adhesion molecule (CAM) interaction
- Cytokine-cytokine receptor interaction
- Hematopoietic cell lineage
- Human T-cell leukemia virus 1 infection
- Human immunodeficiency virus 1 infection
- PD-L1 expression and PD-1 checkpoint pathway in cancer
- Primary immunodeficiency
- T cell receptor signaling pathway
- Th1 and Th2 cell differentiation
- Th17 cell differentiation
- Viral life cycle - HIV-1
- Virion - Human immunodeficiency virus
- Yersinia infection
Associated Diseases (1)
Active Molecules (4)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
GXMWQAXYHFYSNS
|
8.9 | IC50 | 3 | — | |
FRRCHJPQSWYJSH
|
6.9 | IC50 | 4 | — | |
JJGZGELTZPACID
|
6.9 | IC50 | 3 | — | |
SRJIECKMPIRMJJ
|
6.6 | IC50 | 2 | — |