Target Details
| UniProt AC | P01031 |
|---|---|
| Gene Symbol | C5 |
| Protein Name | Complement C5 |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF00207 (A2M) PF07703 (A2M_BRD) PF07677 (A2M_recep) PF01821 (ANATO) PF21309 (C5_CUB) PF17790 (MG1) PF01835 (MG2) PF17791 (MG3) PF17789 (MG4) PF01759 (NTR) PF07678 (TED_complement) |
Summary
- Multi-target molecules 6
- Clinical molecules 1
- Avg pChEMBL 6.17
KEGG Pathways (11)
- Alcoholic liver disease
- Complement and coagulation cascades
- Coronavirus disease - COVID-19
- Herpes simplex virus 1 infection
- Neuroactive ligand-receptor interaction
- Neutrophil extracellular trap formation
- Pertussis
- Prion disease
- Regulation of actin cytoskeleton
- Staphylococcus aureus infection
- Systemic lupus erythematosus
Associated Diseases (1)
Active Molecules (6)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
MLKXDPUZXIRXEP
|
6.2 | Kd | 2 | — | |
PUXBGTOOZJQSKH
|
6.2 | Kd | 3 | — | |
OFPXSFXSNFPTHF
|
6.2 | Kd | 3 | — | |
GZUITABIAKMVPG
|
6.2 | Kd | 22 | Yes | |
KPJVSWMSLFZHBU
|
6.1 | Kd | 3 | — | |
KPJVSWMSLFZHBU
|
6.1 | Kd | 3 | — |