Target Details
UniProt ACP00519
Gene SymbolABL1
Protein NameTyrosine-protein kinase ABL1
OrganismHomo sapiens
Entry Name
Organism Category Human
Pfam Domains PF08919 (F_actin_bind) PF07714 (PK_Tyr_Ser-Thr) PF00017 (SH2) PF00018 (SH3_1)
UniProt
Summary
  • Multi-target molecules 1,419
  • Clinical molecules 468
  • Avg pChEMBL 7.25
KEGG Pathways (12)
Associated Diseases (3)
Top Co-occurrence Targets
Active Molecules (1,419)
InChIKey pChEMBL Type Targets Clinical
JWOJVNKGVGVDHF 7.3 IC50 2 —
KIHQVERTLRHJED 7.3 IC50 3 Yes
KUMLEJXITHSWSP 7.3 IC50 9 Yes
LHCIBQLPMCBTDW 7.3 Kd 3 —
LWFQFYJPBNDMKL 7.3 IC50 2 —
MJXOANVGMNJWLC 7.3 IC50 2 —
MUMGBSXQGWFWJQ 7.3 IC50 2 —
NLXGPUYLEYEZDV 7.3 IC50 2 —
PRPKQKSKLFXCNB 7.3 Ki 2 —
RMHCPURYCHBPLB 7.3 IC50 2 —
VIQMKNOGQPLVRW 7.3 IC50 2 —
VYRBWRJZNBEDCB 7.3 IC50 2 —
WEZBTQCZESWSRP 7.3 IC50 2 —
WJEAROLZOUZMPP 7.3 IC50 2 —
WRXKCNIVRTVEQV 7.3 IC50 2 —
YISURKKUAGVOIV 7.3 IC50 2 —
YJTUMWSGGUZEFI 7.3 IC50 2 —
FRKWMLCUONAHJH 7.2 IC50 13 Yes
HKBVCGJVIFGBEX 7.2 IC50 6 Yes
QSBWHISTPSABIV 7.2 IC50 4 Yes
WRSMBOCJQHDXNC 7.2 IC50 4 —
CAMZXNIVTYLQCA 7.2 IC50 3 —
DDCRNOXQNBDLGB 7.2 IC50 4 Yes
HWZFQQYDALNGQT 7.2 Kd 3 —
JCMWWPAJCOQLAF 7.2 IC50 11 Yes
OHHSWQIUXWNAGL 7.2 IC50 2 —
QEWJRTUCCOIWLO 7.2 IC50 2 —
RJEOZKIUSOFSDC 7.2 IC50 2 —
JZCWLJDSIRUGIN 7.2 Ki 16 —
MVCOAUNKQVWQHZ 7.2 Kd 54 Yes
AQYYPSFZMCKSEL 7.2 IC50 4 Yes
JSPJGKUIWGWCRE 7.2 IC50 5 Yes
MFKUOFHJCWUBET 7.2 Ki 2 Yes
SYMMGQMCJOZALT 7.2 IC50 2 —
YMHOIAKNPORUIV 7.2 IC50 3 —
BLOQVLVYNHGRHT 7.2 IC50 2 —
LCVIRAZGMYMNNT 7.2 Kd 20 —
SIXVDPYFTBZLMQ 7.2 IC50 2 —
ZMSRESYSODUSBK 7.2 IC50 2 —
CHPHDLQQSCKHOK 7.2 IC50 8 Yes
JOOXLOJCABQBSG 7.2 Kd 139 —
NWMPVMMGSHXANZ 7.2 Ki 58 —
QJIVDCJIPGAKQZ 7.2 Ki 25 —
QOSZUVFISSPGCO 7.2 IC50 2 —
XZXHXSATPCNXJR 7.2 Kd 165 Yes
YDOPLCNFRXOHCC 7.2 Ki 28 —
BMCKWRUTJXVUFF 7.2 IC50 4 —
UBFVUIBDLRKUPW 7.2 Ki 2 Yes
BCQMLQGCVHMBRI 7.2 IC50 3 —
BFDYMLHRCBEGCZ 7.2 IC50 2 —
2D structure