Target Details
| UniProt AC | P00519 |
|---|---|
| Gene Symbol | ABL1 |
| Protein Name | Tyrosine-protein kinase ABL1 |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF08919 (F_actin_bind) PF07714 (PK_Tyr_Ser-Thr) PF00017 (SH2) PF00018 (SH3_1) |
Summary
- Multi-target molecules 1,419
- Clinical molecules 468
- Avg pChEMBL 7.25
KEGG Pathways (12)
Associated Diseases (3)
Active Molecules (1,419)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
OLGSVSPNJXGSAD
|
10.2 | Ki | 5 | Yes | |
VYEYNLSRVXXGPW
|
10.0 | Ki | 2 | — | |
NFTNUHHJWIJBRN
|
10.0 | IC50 | 3 | — | |
QCFZDYFUWADUJV
|
9.8 | IC50 | 3 | — | |
CZHIVNNGAXNFBN
|
9.8 | Kd | 3 | — | |
OHGOKRHLLKPKJK
|
9.8 | Kd | 3 | — | |
QAHANVZHNDZWSM
|
9.8 | IC50 | 3 | — | |
UPXFBKXBRDBIKU
|
9.8 | IC50 | 3 | — | |
UVMSVIJGLODSFN
|
9.8 | IC50 | 3 | — | |
VQQKESJQSNYQOP
|
9.8 | IC50 | 3 | — | |
YXCVYRQZUTUYKZ
|
9.7 | IC50 | 3 | — | |
JCNSIZBVFFVTJE
|
9.7 | IC50 | 3 | — | |
UGRGTNDQCIYUDE
|
9.7 | IC50 | 3 | — | |
OWEGQACAHYGLOT
|
9.7 | IC50 | 3 | — | |
RBQXHLBIJMHVHI
|
9.7 | Kd | 3 | — | |
LPJDSINAEJVSNX
|
9.7 | IC50 | 6 | Yes | |
BDDFTQKLPQWOLD
|
9.6 | IC50 | 3 | — | |
CJXZIWDVXAJFBP
|
9.6 | IC50 | 3 | — | |
FGTNRYWAENEKJL
|
9.6 | Kd | 3 | — | |
KUTDZECNFUUAHC
|
9.6 | IC50 | 3 | — | |
RRDDKVJWDOIIFN
|
9.6 | IC50 | 3 | — | |
VDVSFLZBRCBQIQ
|
9.6 | IC50 | 3 | — | |
DAAOYHIERMVREX
|
9.6 | IC50 | 3 | — | |
ULMCFLZUGRSEQA
|
9.6 | Ki | 17 | — | |
CHYCQBZNTKXHMV
|
9.6 | IC50 | 3 | — | |
KVDHKHPORALHHP
|
9.6 | Kd | 3 | — | |
SUXYGJZMCWKJJI
|
9.6 | IC50 | 26 | Yes | |
LTQIPTSOJUTHQH
|
9.5 | IC50 | 3 | — | |
GZNVXAZGAACUQD
|
9.5 | IC50 | 2 | — | |
NXTAONONNMIHOO
|
9.5 | Ki | 3 | — | |
IGTIROPAMADUPR
|
9.5 | IC50 | 2 | — | |
TZKBVRDEOITLRB
|
9.5 | Kd | 7 | — | |
UDTHXJUPBYEYMC
|
9.4 | IC50 | 2 | — | |
OVTAMJUJNVINGX
|
9.4 | IC50 | 2 | — | |
ANUHLKPVOXDYSK
|
9.4 | IC50 | 5 | Yes | |
BGKZQFXBRTXGLE
|
9.4 | Ki | 2 | — | |
VSJSIOZQNZPUAV
|
9.4 | IC50 | 3 | — | |
XTMQXGYZVJVLMD
|
9.4 | IC50 | 3 | Yes | |
YDHFUBCYRHHRFM
|
9.4 | IC50 | 2 | — | |
GNOXITMWGVMUID
|
9.4 | Kd | 3 | — | |
SRUDWIBMRKZRQG
|
9.4 | IC50 | 2 | — | |
ZKQTVBGLURSDIR
|
9.4 | Ki | 2 | — | |
HBMCAYMASSWIBL
|
9.4 | IC50 | 3 | Yes | |
MEBNSJCLFXPYII
|
9.4 | IC50 | 3 | Yes | |
XHRFFDAZHQMDPM
|
9.4 | IC50 | 3 | Yes | |
IFVGNYDOUDEVPK
|
9.4 | IC50 | 3 | — | |
JBMSSKLUVBBAHN
|
9.4 | Kd | 3 | — | |
OHFRVFUEGWQWTA
|
9.3 | IC50 | 2 | — | |
WKTHEPAGRCQCOF
|
9.3 | IC50 | 2 | — | |
JCNVRKBMXOPADG
|
9.3 | Ki | 2 | — |