Target Details
UniProt ACO96017
Gene SymbolCHEK2
Protein NameSerine/threonine-protein kinase Chk2
OrganismHomo sapiens
Entry Name
Organism Category Human
Pfam Domains PF00498 (FHA) PF00069 (Pkinase)
UniProt
Summary
  • Multi-target molecules 237
  • Clinical molecules 36
  • Avg pChEMBL 6.89
KEGG Pathways (4)
Associated Diseases (4)
Top Co-occurrence Targets
Active Molecules (237)
InChIKey pChEMBL Type Targets Clinical
ZOKAHENGMGWPOX 6.1 IC50 2 Yes
ACLLLJSNOCYQOJ 6.1 IC50 8 —
JWNPDZNEKVCWMY 6.1 Kd 57 Yes
KGMVZSJAPXYTKH 6.0 IC50 23 —
AWDORCFLUJZUQS 6.0 Ki 22 —
CFBADDSSFSYJPF 6.0 Ki 23 —
CQBBMNXXVMOFCA 6.0 Ki 39 —
GQGMUKOYILWOIQ 6.0 Ki 25 —
HTROFVQKJODSCL 6.0 Ki 11 —
IVVSBEQDCAZLFY 6.0 IC50 333 —
JAMDNXUAYUHJLJ 6.0 Ki 40 —
KHVVJKLNKLQLJZ 6.0 IC50 288 —
MAHFVAHPQSLLJF 6.0 IC50 288 —
NFMGZVPRGVERNN 6.0 Ki 44 —
NHEQNFWGPSKRMJ 6.0 Ki 7 —
SOVYWBOZOBVFLP 6.0 Ki 10 —
SRUYMJRFVGLQDV 6.0 Ki 37 —
UKJCXJDXVXDGMI 6.0 IC50 2 —
UWQBVYXTLXNIOO 6.0 Ki 10 —
VXYDJXMHISGSDA 6.0 Ki 59 —
ZPVLRSVLOWVDJC 6.0 Ki 14 —
AZTMYWWWILJAKW Clinical TTD_MultiTarget 16 Yes
BPNUQXPIQBZCMR Clinical TTD_MultiTarget 83 Yes
HHUFICWXHSFBHG Clinical TTD_MultiTarget 2 Yes
JJJZVISMHBIATR Clinical TTD_MultiTarget 2 Yes
KAJIDAUQCMSGGN Clinical TTD_MultiTarget 8 Yes
MYHOUKHXSVKHBA Clinical TTD_MultiTarget 3 Yes
MZPDPRITYJNRSG Clinical TTD_MultiTarget 8 Yes
OSFGHYZLBDAJTP Clinical TTD_MultiTarget 3 Yes
OWXORKPNCHJYOF Clinical TTD_MultiTarget 17 Yes
SQUBJXXBYMPOFW Clinical TTD_MultiTarget 6 Yes
UIQYGXADJQWKAB Clinical TTD_MultiTarget 2 Yes
VKPCXCHYSBVEMW Clinical TTD_MultiTarget 2 Yes
WXUJAQBSBZLVEV Clinical TTD_MultiTarget 3 Yes
YXCWBNCDJZEBKY Clinical TTD_MultiTarget 5 Yes
ZAIOSQVVOKXAEK Clinical TTD_MultiTarget 2 Yes
ZTKSRYFKEVGMFY Clinical TTD_MultiTarget 2 Yes
2D structure