Target Details
| UniProt AC | O95835 |
|---|---|
| Gene Symbol | LATS1 |
| Protein Name | Serine/threonine-protein kinase LATS1 |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF00069 (Pkinase) PF00433 (Pkinase_C) PF00627 (UBA) |
Summary
- Multi-target molecules 87
- Clinical molecules 7
- Avg pChEMBL 8.43
KEGG Pathways (3)
Active Molecules (87)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
DTVNECWMYCSEBL
|
11.2 | Ki | 2 | — | |
SAQSMANEGRAMNT
|
11.2 | Ki | 2 | — | |
JQAXPHDIJOQPBP
|
11.2 | Ki | 2 | — | |
SAQSMANEGRAMNT
|
11.2 | Ki | 2 | — | |
DTVNECWMYCSEBL
|
11.1 | Ki | 2 | — | |
WEAHURJZQJBTGH
|
11.1 | Ki | 2 | — | |
SXOIZZVBAAACIQ
|
11.0 | Ki | 2 | — | |
UAPFATLGRSUIKX
|
10.9 | Ki | 2 | — | |
SYHRTOREQDHSNY
|
10.3 | Ki | 2 | — | |
PANBXEPRTUWMHA
|
10.3 | Ki | 2 | — | |
MYPGOQOVEQKGDN
|
9.2 | IC50 | 2 | — | |
ACTDLFQRJKPKFQ
|
9.0 | IC50 | 2 | — | |
AFJHACZNTJKCIF
|
9.0 | IC50 | 2 | — | |
CHYCCNFSSCTALZ
|
9.0 | IC50 | 2 | — | |
JDMAQIORUXZAGZ
|
9.0 | IC50 | 2 | — | |
KCWQIAOSJJWFIG
|
9.0 | IC50 | 2 | — | |
LMLFNPDYWJFFPD
|
9.0 | IC50 | 2 | — | |
MGSXOJRYNIPSTE
|
9.0 | IC50 | 2 | — | |
OJKBHNAVTDJSIO
|
9.0 | IC50 | 2 | — | |
OLUIHIBCEWNDET
|
9.0 | IC50 | 2 | — | |
PGOCRNZIASOKRK
|
9.0 | IC50 | 2 | — | |
PTTKHXBEPPAXSE
|
9.0 | IC50 | 2 | — | |
QLNKJSSYMWYESY
|
9.0 | IC50 | 2 | — | |
RGIKJUZEMMTILQ
|
9.0 | IC50 | 2 | — | |
RQCQSMAAAMSVHQ
|
9.0 | IC50 | 2 | — | |
UFYSVZDHPHLSEY
|
9.0 | IC50 | 2 | — | |
VCWNZJZLJJLTBZ
|
9.0 | IC50 | 2 | — | |
VJFDDNKVWALCBK
|
9.0 | IC50 | 2 | — | |
YXFRTVUVQNPAHF
|
9.0 | IC50 | 2 | — | |
BEZHNWWMIVIPFV
|
8.9 | IC50 | 2 | — | |
GSFWSEGLHKYRGG
|
8.9 | IC50 | 2 | — | |
ZCCPLJOKGAACRT
|
8.8 | Kd | 599 | — | |
CCJRVCDZHWNBTA
|
8.7 | IC50 | 2 | — | |
DCIPFXLSLUFVQA
|
8.7 | IC50 | 2 | — | |
GMBDJMAWOMXCHX
|
8.7 | IC50 | 2 | — | |
GTDNROOVOBKLDL
|
8.7 | IC50 | 2 | — | |
HQFDCITUHVQXEV
|
8.7 | IC50 | 2 | — | |
JJNZJRXOAFOQOK
|
8.7 | IC50 | 2 | — | |
OCRGFIAWWYJUTP
|
8.7 | IC50 | 2 | — | |
SBPQHDLJGZBWTL
|
8.7 | IC50 | 2 | — | |
SBPQHDLJGZBWTL
|
8.7 | IC50 | 2 | — | |
WKYHVIILYCJVBF
|
8.7 | IC50 | 2 | — | |
KSKYRXFKNPXFGI
|
8.6 | IC50 | 6 | — | |
GPKFECYSQTWZCI
|
8.5 | IC50 | 2 | — | |
IKOCQBSJIXAKFW
|
8.5 | IC50 | 2 | — | |
IZKUFWOXLYUAAV
|
8.5 | IC50 | 2 | — | |
JVCDXTHYVYGMQC
|
8.5 | IC50 | 2 | — | |
MBMKHDKGWLLWJM
|
8.5 | IC50 | 2 | — | |
PTPZOJYJIOCLLO
|
8.5 | IC50 | 2 | — | |
WIFZIPRZHKCGGL
|
8.5 | IC50 | 2 | — |