TNKS — MultiTargetDB

Target Details

UniProt AC	`O95271`
Gene Symbol	TNKS
Protein Name	Poly [ADP-ribose] polymerase tankyrase-1
Organism	Homo sapiens
Entry Name
Organism Category	Human
Pfam Domains	PF00023 (Ank) PF12796 (Ank_2) PF00644 (PARP) PF07647 (SAM_2)

Summary

Multi-target molecules 711
Clinical molecules 0
Avg pChEMBL 7.76

Top Co-occurrence Targets

TNKS2 695 shared
PARP1 116 shared
PARP2 95 shared
PARP3 13 shared
WNT3A 12 shared
PARP4 7 shared
PARP12 7 shared
TIPARP 7 shared
PARP10 6 shared
MAOB 6 shared

Active Molecules (711)

InChIKey	pChEMBL	Type	Targets	Clinical
`GPNUQNSOOWDVCV`	7.5	IC50	2	—
`GWXCGEJJQFHPPA`	7.5	IC50	2	—
`GYUXFBLUWQVRKE`	7.5	IC50	2	—
`JAQISDRQXHHOJS`	7.5	IC50	2	—
`ZEMGNPBLWCWPSA`	7.5	IC50	2	—
`IHBILSNANZVSHM`	7.5	IC50	2	—
`NSQTWPGTGYHDIM`	7.5	IC50	3	—
`RVVUDOUAVPTCLH`	7.5	IC50	2	—
`UVPFWJCKEJKCCW`	7.5	IC50	2	—
`YIGLQGYCCCNBJG`	7.5	IC50	3	—
`MMVLLPFESXFQML`	7.5	IC50	2	—
`QAPCSHKKOSUOHO`	7.5	IC50	2	—
`RJVXWJADDFXFIL`	7.5	IC50	2	—
`FMURKSCWRQGCFO`	7.5	IC50	2	—
`GJNUBEZCTKBVCJ`	7.5	IC50	2	—
`MMWOCAKTGVKRBA`	7.5	IC50	2	—
`QWYIBGOLIBASGM`	7.5	IC50	2	—
`CWSRZPPZHBSBKK`	7.5	IC50	2	—
`CYTPHLGUFRTMFU`	7.5	IC50	2	—
`HANJAZOKICPNAX`	7.5	IC50	3	—
`IMXDGAQYSOUZNJ`	7.5	IC50	2	—
`YAAIOGGCMLWOPM`	7.5	IC50	4	—
`CVRMLBHUCXVUNB`	7.5	IC50	2	—
`GDPXXNADTSHZLW`	7.5	IC50	2	—
`HMPAJUGZRUZDQJ`	7.5	IC50	2	—
`NGWLKFVMSQZGRO`	7.5	IC50	3	—
`RFMIZKCQNUDSTO`	7.5	IC50	3	—
`SMUYIABTVDLDHO`	7.5	IC50	2	—
`UDFQFCRUNLBZKM`	7.5	IC50	3	—
`VKQCBCMAFAIWOE`	7.5	IC50	3	—
`ZBJVKCDYVCVOIF`	7.5	IC50	3	—
`ZHJZIKXPWBLJFI`	7.5	IC50	2	—
`ZPLCRPBMZNZKDA`	7.5	IC50	2	—
`SSDOGFZFEYCRRH`	7.5	IC50	2	—
`FICOSMQGCGGNKM`	7.4	IC50	2	—
`GNYGUGSAEOIONU`	7.4	IC50	2	—
`KZUPFZKALLNBBV`	7.4	IC50	2	—
`NFZIFTVDVOZOII`	7.4	IC50	2	—
`NVYDBKBQXGPVQD`	7.4	IC50	2	—
`ODDUCZHVBOGEBZ`	7.4	IC50	2	—
`PERWUJINIMBCAY`	7.4	IC50	2	—
`DDIZJESACWEABB`	7.4	IC50	2	—
`DUYFEUQQISPFMM`	7.4	IC50	2	—
`DYSYSZSIEJMTPV`	7.4	IC50	2	—
`FAAVFGPJNCDFEN`	7.4	IC50	2	—
`HNYALLOQJOASHW`	7.4	IC50	2	—
`HTLUBFSSIMOABR`	7.4	IC50	3	—
`KBFBQODMTQIXEB`	7.4	IC50	3	—
`OUQKWLCWNMVJML`	7.4	IC50	2	—
`RXWZXVGCPOUNQT`	7.4	IC50	3	—