Target Details
UniProt ACO95267
Gene SymbolRASGRP1
Protein NameRAS guanyl-releasing protein 1
OrganismHomo sapiens
Entry Name
Organism Category Human
Pfam Domains PF00130 (C1_1) PF00617 (RasGEF) PF00618 (RasGEF_N)
Summary
  • Multi-target molecules 13
  • Clinical molecules 0
  • Avg pChEMBL 7.88
Associated Diseases (1)
Top Co-occurrence Targets
Active Molecules (13)
InChIKey pChEMBL Type Targets Clinical
SIWILCBNYOGJQH 9.4 Ki 4
YHESSERBDSKRDZ 9.4 Ki 4
ZETICKHKBWHSEB 9.2 Ki 4
FKPDQMIETMHJBH 9.1 Ki 4
DDBJOZVQHUZKJJ 8.8 Ki 4
JSXUDEUMWQFINT 7.6 Ki 3
OBNHABKOCPUFDD 7.6 Ki 3
JSXUDEUMWQFINT 7.5 Ki 3
OBNHABKOCPUFDD 7.4 Ki 3
WMOCKUYLGCVFJM 7.2 Ki 3
GNIYOZALILMSSH 6.9 Ki 3
RRGGCASWPGLJTK 6.2 Ki 3
UIOPZRFPFXYNME 6.2 Ki 3
2D structure