Target Details
| UniProt AC | O75907 |
|---|---|
| Gene Symbol | DGAT1 |
| Protein Name | Diacylglycerol O-acyltransferase 1 |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF03062 (MBOAT) |
Summary
- Multi-target molecules 52
- Clinical molecules 0
- Avg pChEMBL 7.72
KEGG Pathways (4)
Associated Diseases (1)
Active Molecules (52)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
OZXNUTGMCCPZLB
|
10.0 | IC50 | 2 | — | |
FYBZEJITZIQBMD
|
9.2 | IC50 | 2 | — | |
VIESBBSLVITZSP
|
9.2 | IC50 | 2 | — | |
WWRMGEDPNSSUKN
|
8.9 | IC50 | 2 | — | |
AGRCWMNPRAQACR
|
8.8 | IC50 | 2 | — | |
KBWITEUFTUYLBH
|
8.8 | IC50 | 2 | — | |
NGEBYTLALFOQKI
|
8.7 | IC50 | 2 | — | |
VOSAIVRHKRLIFT
|
8.7 | IC50 | 2 | — | |
XIZUPZJXAGWJEG
|
8.6 | IC50 | 2 | — | |
UHGARPFLDTVCMI
|
8.6 | IC50 | 2 | — | |
SKTLSADQZOHVDO
|
8.5 | IC50 | 2 | — | |
YYEOGOCGDPAYFM
|
8.5 | IC50 | 2 | — | |
GRPOVCVXFWOXGL
|
8.5 | IC50 | 2 | — | |
ZSOYHMGKJFRGOK
|
8.4 | IC50 | 2 | — | |
OOQXFUAGTTVNNH
|
8.4 | IC50 | 2 | — | |
MWKSRKSEWLRPBL
|
8.3 | Kd | 1075 | — | |
OFNQWTBYWOSMLZ
|
8.3 | IC50 | 2 | — | |
KZCATALIKGTHNO
|
8.2 | IC50 | 2 | — | |
UNWXUCUCEFLFIK
|
8.2 | IC50 | 2 | — | |
JBPKLRDXEWMGAS
|
8.1 | IC50 | 2 | — | |
LVXCTBHTIRUVQQ
|
8.1 | IC50 | 2 | — | |
NYWZECIITKJGMY
|
8.1 | IC50 | 2 | — | |
KMRKVWIQPVPEED
|
8.0 | IC50 | 2 | — | |
XOFGTUXJGBWWCZ
|
7.8 | IC50 | 2 | — | |
YXFNPRHZMOGREC
|
7.6 | IC50 | 2 | — | |
YXFNPRHZMOGREC
|
7.6 | IC50 | 2 | — | |
MSUFBWVSDWBCPP
|
7.5 | IC50 | 2 | — | |
FNWZYYCFELRHJC
|
7.5 | IC50 | 2 | — | |
LFHXTDBDALXSLW
|
7.5 | IC50 | 2 | — | |
KQTNPRUSWDICFO
|
7.4 | IC50 | 2 | — | |
DFLCDDOFQUFQBZ
|
7.3 | IC50 | 2 | — | |
MXPRNVBVWZYUBT
|
7.3 | IC50 | 2 | — | |
QDPMKFBXXQYKOZ
|
7.3 | IC50 | 2 | — | |
IKTGWCGZNVABQC
|
7.2 | IC50 | 2 | — | |
PUQLADUSPHHAJY
|
7.2 | IC50 | 2 | — | |
OWDDNHIUYZNNIU
|
7.2 | IC50 | 2 | — | |
NPIULHQZTJCEEG
|
7.2 | IC50 | 2 | — | |
RCGUJMAODPHJSP
|
7.2 | IC50 | 2 | — | |
KYOXLEZIYMUPQI
|
7.1 | IC50 | 2 | — | |
JQPWLGSLPUPUQJ
|
7.0 | IC50 | 2 | — | |
NBXLBDCDGRUOCF
|
7.0 | IC50 | 2 | — | |
YQOCGVRFFGLKAK
|
7.0 | IC50 | 2 | — | |
SKEBJINBVARVMV
|
6.9 | IC50 | 2 | — | |
AQCJSILNHNZZTF
|
6.9 | IC50 | 2 | — | |
IQQINCDOMBDJPM
|
6.8 | IC50 | 2 | — | |
LAAVMNDRWKHIJC
|
6.7 | IC50 | 2 | — | |
RVQTWWBCQFZCAA
|
6.6 | IC50 | 2 | — | |
ZEJKWPIVLDNVQT
|
6.6 | IC50 | 2 | — | |
FKKNNKHSCLMIDP
|
6.5 | IC50 | 2 | — | |
IVWQWIXVZOTSHG
|
6.5 | IC50 | 2 | — |