Target Details
| UniProt AC | O75489 |
|---|---|
| Gene Symbol | NDUFS3 |
| Protein Name | NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF00329 (Complex1_30kDa) |
Summary
- Multi-target molecules 3
- Clinical molecules 0
- Avg pChEMBL 6.93
KEGG Pathways (13)
- Alzheimer disease
- Amyotrophic lateral sclerosis
- Chemical carcinogenesis - reactive oxygen species
- Diabetic cardiomyopathy
- Huntington disease
- Metabolic pathways
- Non-alcoholic fatty liver disease
- Oxidative phosphorylation
- Parkinson disease
- Pathways of neurodegeneration - multiple diseases
- Prion disease
- Retrograde endocannabinoid signaling
- Thermogenesis
Associated Diseases (1)
Active Molecules (3)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
MWKSRKSEWLRPBL
|
8.7 | Kd | 1075 | — | |
INDTZNYQNROCGV
|
6.1 | IC50 | 50 | — | |
YRFIJMKHSNJANR
|
6.0 | IC50 | 50 | — |