KDM1A — MultiTargetDB

Target Details

UniProt AC	`O60341`
Gene Symbol	KDM1A
Protein Name	Lysine-specific histone demethylase 1A
Organism	Homo sapiens
Entry Name
Organism Category	Human
Pfam Domains	PF01593 (Amino_oxidase) PF04433 (SWIRM)

Summary

Multi-target molecules 721
Clinical molecules 0
Avg pChEMBL 7.55

KEGG Pathways (1)

Thermogenesis

Associated Diseases (2)

Top Co-occurrence Targets

HDAC1 241 shared
HDAC8 152 shared
RCOR1 149 shared
GSTP1 136 shared
HDAC6 121 shared
MAOA 58 shared
MAOB 33 shared
EZH2 10 shared
EHMT2 4 shared
HDAC2 4 shared

Active Molecules (721)

InChIKey	pChEMBL	Type	Targets	Clinical
`UOFRHGBXPLIKES`	7.5	IC50	3	—
`XNQZFSJVCNUUMR`	7.5	IC50	2	—
`HDVDLEPVLVTECB`	7.5	IC50	2	—
`PWPKPNWKBRXCMZ`	7.5	IC50	2	—
`PGGZITRPPUEJHH`	7.5	IC50	2	—
`SRNUZUYKHZOGFL`	7.5	IC50	2	—
`CVPCLIKFVRZOSV`	7.5	IC50	2	—
`CVPCLIKFVRZOSV`	7.5	IC50	2	—
`JTYCUBANCFAWDT`	7.5	IC50	2	—
`UHNJBSOSHGEQJU`	7.5	IC50	2	—
`YXTYPKDXCRBOFD`	7.5	IC50	3	—
`MGNMJTQYYGMLMX`	7.5	IC50	2	—
`TVYIZPPTJYFBQU`	7.5	IC50	2	—
`WVZVIGFERDHWIL`	7.5	IC50	2	—
`HLHUFXWETVNBDN`	7.5	IC50	3	—
`IEFMRNLTUCWGOZ`	7.5	IC50	2	—
`IMBGXADCPYZGAE`	7.5	IC50	2	—
`LMSFGWYBIGVSHX`	7.5	IC50	2	—
`QCWJSKPFTMLIKX`	7.5	IC50	2	—
`ZCXOEWQARFTSEU`	7.5	IC50	2	—
`ZFWZJXPRYBXQIV`	7.5	IC50	2	—
`SNYUIWMNWQHODY`	7.5	IC50	2	—
`UGYBNTNFUXFKEE`	7.5	IC50	2	—
`XYAZRGFFUVDRRE`	7.5	IC50	2	—
`WCXPBVOVDHIWAO`	7.5	IC50	2	—
`WYPKDPDLLLOYCQ`	7.5	IC50	2	—
`ZEANRRHZHNEUOD`	7.5	IC50	2	—
`NQMHPFOQSZMEJJ`	7.4	IC50	2	—
`RETHRNCONJQITP`	7.4	IC50	2	—
`CSQCLYDAJSRUEL`	7.4	IC50	2	—
`FVUKYUBBWHTHQT`	7.4	IC50	2	—
`GADXVPHSTSJKLA`	7.4	IC50	2	—
`PGGZITRPPUEJHH`	7.4	IC50	2	—
`WJUINCYWBXZRNH`	7.4	IC50	2	—
`BEDVSZSKZCEAIN`	7.4	IC50	2	—
`FQTSWPYJJOYHIH`	7.4	IC50	2	—
`OJCTVINEUNWRJO`	7.4	IC50	2	—
`AORRFKCUHQJLBK`	7.4	Ki	2	—
`HPMSXSJJPUNVQO`	7.4	IC50	3	—
`JIDRFGPRVMTCQJ`	7.4	IC50	3	—
`NDNVIFQCNJINSJ`	7.4	IC50	2	—
`VLAPFESAHIUASX`	7.4	IC50	3	—
`SJYSQOJGPMLVJQ`	7.4	IC50	2	—
`ARGUJKCXVXGQFI`	7.4	IC50	2	—
`BASFYRLYJAZPPL`	7.4	IC50	2	—
`YIHUNTSCCUBOJN`	7.4	IC50	2	—
`AKVGPXPMMTUBST`	7.4	IC50	2	—
`ARHXOWDEHGDIPR`	7.4	IC50	2	—
`FFYJSQJRMOFPKF`	7.4	IC50	3	—
`RHYDLZPXYPVUIP`	7.4	IC50	2	—