Target Details
| UniProt AC | O43677 |
|---|---|
| Gene Symbol | NDUFC1 |
| Protein Name | NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF15088 (NADH_dh_m_C1) |
Summary
- Multi-target molecules 2
- Clinical molecules 0
- Avg pChEMBL 6.05
KEGG Pathways (13)
- Alzheimer disease
- Amyotrophic lateral sclerosis
- Chemical carcinogenesis - reactive oxygen species
- Diabetic cardiomyopathy
- Huntington disease
- Metabolic pathways
- Non-alcoholic fatty liver disease
- Oxidative phosphorylation
- Parkinson disease
- Pathways of neurodegeneration - multiple diseases
- Prion disease
- Retrograde endocannabinoid signaling
- Thermogenesis
Active Molecules (2)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
INDTZNYQNROCGV
|
6.1 | IC50 | 50 | — | |
YRFIJMKHSNJANR
|
6.0 | IC50 | 50 | — |