HCRTR1 — MultiTargetDB

Target Details

UniProt AC	`O43613`
Gene Symbol	HCRTR1
Protein Name	Orexin/Hypocretin receptor type 1
Organism	Homo sapiens
Entry Name
Organism Category	Human
Pfam Domains	PF00001 (7tm_1)

Summary

Multi-target molecules 3,881
Clinical molecules 0
Avg pChEMBL 7.32

KEGG Pathways (2)

Top Co-occurrence Targets

HCRTR2 3872 shared
OPRK1 8 shared
OPRD1 4 shared
OPRM1 4 shared
TSPO 2 shared
ALOX15 2 shared
CYP3A4 2 shared
ENPP2 1 shared
HTR2B 1 shared
ADORA2A 1 shared

Active Molecules (3,881)

InChIKey	pChEMBL	Type	Targets	Clinical
`AEIDDRZWBROWDG`	8.5	IC50	2	—
`ALLRFJYWSLYPOG`	8.5	IC50	2	—
`AWYCCGHIHBHRDF`	8.5	IC50	2	—
`AXADJOXVBYMSJX`	8.5	IC50	2	—
`BBSRUMBWTMTJBM`	8.5	Ki	2	—
`BGQITKZOLNRSMS`	8.5	Ki	2	—
`BHVUTIRHZGGMHB`	8.5	IC50	2	—
`BMOOSZNCYAPHJA`	8.5	Ki	2	—
`BRUXZKWUDDEDNK`	8.5	IC50	2	—
`BXGAQSCKCCBJHO`	8.5	Ki	2	—
`CLEHSUGXBFEAJH`	8.5	Ki	2	—
`CMHXDZPNJZYWHC`	8.5	IC50	2	—
`CXGGFUAERWUYLI`	8.5	IC50	2	—
`DEVWYCIKDYFHKV`	8.5	IC50	2	—
`DTGKMEOSLSJFKU`	8.5	Ki	2	—
`DUUOWDLWEJVCSI`	8.5	IC50	2	—
`FIIIFGLLUUQWSJ`	8.5	IC50	2	—
`FJYYNLJIKKPGEW`	8.5	IC50	2	—
`FMAOIOLKTPUQSK`	8.5	IC50	2	—
`FZZMSUDTQOQSBH`	8.5	IC50	2	—
`GFLJEIYYKHTWBI`	8.5	Ki	2	—
`GQTXCZZVJJMWEW`	8.5	Ki	2	—
`GXJCYIJGXFIRTG`	8.5	Ki	2	—
`HBSKMUVHZAPPQG`	8.5	IC50	2	—
`HENXYXVXSIGXOV`	8.5	IC50	2	—
`HWCNAOSLUJKVML`	8.5	IC50	2	—
`HWYITMBMUBDYTG`	8.5	IC50	2	—
`HZTIXYMNAITACJ`	8.5	IC50	2	—
`IARRCNRCFRHKHB`	8.5	IC50	2	—
`IEHBRXSPEXUDES`	8.5	IC50	2	—
`JIEFEDOEWSOKJT`	8.5	Ki	2	—
`JOKDLAIJHCOJRF`	8.5	IC50	2	—
`KXYYELXHLGICGL`	8.5	IC50	2	—
`LAINVSFGRYRKDA`	8.5	IC50	2	—
`LBFKZBXOXQSKDO`	8.5	IC50	2	—
`LCOLPIYEEOVJIY`	8.5	IC50	2	—
`LNVMEGYQWMZUBX`	8.5	IC50	2	—
`LOYYUSOWAAROMT`	8.5	IC50	2	—
`LUSDGIQGCBLNQS`	8.5	IC50	2	—
`MUBSGJOPYBKNEH`	8.5	IC50	2	—
`MXAFQLDZSLKFSZ`	8.5	IC50	2	—
`NJMICVQAQQXLQH`	8.5	IC50	2	—
`NNBZSPNSBCOMJO`	8.5	IC50	2	—
`NZBAPJBYGIRLSE`	8.5	IC50	2	—
`NZVFTQSJWLBCIO`	8.5	IC50	2	—
`PCALLGUMHPYDBK`	8.5	Kd	2	—
`PHEQMGRTEIENAJ`	8.5	IC50	2	—
`PYDZIRFKTNHXGE`	8.5	IC50	2	—
`PYRHLDRQRCTVES`	8.5	IC50	2	—
`QGANVXHHDNOJNO`	8.5	IC50	2	—